Comparing two types of shoulder replacement surgeries

From Cuff Arthropathy to Reverse Shoulder Arthroplasty - a Multicentre Randomized Control Trial (Study 1: Does BIO-RSA Provides Superior Clinical Outcome Compared to Conventional RSA?).

Not applicable Interventional Lovisenberg Diakonale Hospital · NCT06025331

This study is testing whether a new type of shoulder replacement surgery can help people with shoulder arthritis do better and have fewer problems than the standard surgery.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment130 (estimated)
Ages45 Years to 80 Years
SexAll
SponsorLovisenberg Diakonale Hospital Academic / other
Locations2 sites (Skien, Telemark and 1 other locations)
Trial IDNCT06025331 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to compare the outcomes of two different reverse shoulder arthroplasties: a conventional reverse shoulder arthroplasty (RSA) and a lateralized version known as BIO-RSA. The study will assess the functional results and complications experienced by patients after two years of surgery. By lateralizing the center of rotation in the BIO-RSA, researchers hope to improve range of motion and stability while reducing complications such as scapular notching. The trial will involve 130 patients across four hospitals, providing valuable insights into the best treatment options for shoulder osteoarthritis and related conditions.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals eligible for primary reverse shoulder arthroplasty due to osteoarthritis or related conditions.

Not a fit: Patients with severe osteoporosis, dementia, or those requiring revision surgery may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved surgical outcomes and quality of life for patients undergoing shoulder replacement surgery.

How similar studies have performed: While there have been studies on reverse shoulder arthroplasty, the specific approach of lateralizing the center of rotation with BIO-RSA is relatively novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Eligible for primary RSA due to OA, massive RC tear, failed RC repair or post-instability osteoarthritis
* Able to read or write Norwegian

Exclusion Criteria:

* Severe osteoporosis
* Osteonecrosis of the humeral head
* Dementia
* Poor deltoid function
* Revision surgery
* ASA IV
* Suspected chronic infection
* Acute fracture

Where this trial is running

Skien, Telemark and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Arthroplasty, Replacement, ShoulderShoulder OsteoarthritisReverse Shoulder ArthroplastyBIO-RSAOrthopedic surgery
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.