Comparing two types of nerve blocks for wrist fracture treatment
Brachial Plexus Nerve Block Versus Haematoma Block for Closed Reduction of Distal Radius Fracture in Adults - The BLOCK Trial. A Multicentre Randomised Controlled Trial.
This study tests which type of anesthesia works better for pain relief in adults getting treatment for wrist fractures without surgery.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 1716 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Nordsjaellands Hospital Academic / other |
| Locations | 1 site (Hillerød, Capital Region) |
| Trial ID | NCT06678438 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates the effectiveness and safety of a brachial plexus nerve block compared to standard haematoma block anesthesia for adults undergoing closed reduction of distal radius fractures. Participants will receive one of the two types of anesthesia to facilitate the realignment of fractured bone fragments without surgical intervention. The study aims to determine which method provides better pain relief and overall outcomes during the procedure.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older with a distal radius fracture requiring closed reduction.
Not a fit: Patients with fractures that require surgical intervention or have contraindications to the trial medications may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management and recovery for patients with wrist fractures.
How similar studies have performed: Other studies have shown promising results with nerve blocks for similar procedures, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults (age ≥ 18 years) with a distal radius fracture in need of closed reduction Exclusion Criteria: * Patients who would never qualify for surgery according to local guidelines * Lack of informed consent * No Danish Central Person Register (CPR) number * Allergies to the trial medication * Distal radius fracture initially deemed to require surgery regardless of the outcome of the closed reduction * Open fractures (fracture-related wound requiring sutures) * Other fractures on the same extremity ((NOT including distal ulna fracture(s)) * Bilateral distal radius fractures both requiring closed reduction * Concomitant medical or surgical condition taking priority over the closed reduction of the distal radius fracture.
Where this trial is running
Hillerød, Capital Region
- Copenhagen University Hospital - North Zealand Hillerød — Hillerød, Capital Region, Denmark (Recruiting)
Study contacts
- Principal investigator: Cecilie D Harwood, MD, PhD-fellow — Copenhagen University Hospital - North Zealand
- Study coordinator: Cecilie D Harwood, MD, PhD-fellow
- Email: cecilie.dupont.harwood.01@regionh.dk
- Phone: 48 29 20 12
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.