Comparing two types of nerve blocks for pain relief after lung surgery

A Comparative Study Between Ultrasound Guided Thoracic Paravertebral Block VS Ultrasound Guided Serrartus Anterior Muscle Block in Video-assisted Thoracoscopic Surgeries.

Not applicable Interventional Ain Shams University · NCT05971368

This study is testing which of two types of nerve blocks works better for pain relief after lung surgery to help patients recover faster and use fewer pain medications.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment80 (estimated)
Ages20 Years to 65 Years
SexAll
SponsorAin Shams University Academic / other
Locations1 site (Cairo, Abbasia)
Trial IDNCT05971368 on ClinicalTrials.gov

What this trial studies

This study compares the effectiveness of ultrasound-guided thoracic paravertebral block versus serratus anterior muscle block for managing postoperative pain in patients undergoing video-assisted thoracoscopic surgery (VATS). Both techniques aim to provide effective pain relief while minimizing the use of opioids, thus facilitating quicker recovery. Patients aged 20 to 65 with ASA physical status I to II will be included, and the interventions will involve administering bupivacaine (0.25%) using ultrasound guidance. The study seeks to determine which method offers superior analgesia post-surgery.

Who should consider this trial

Good fit: Ideal candidates are patients aged 20 to 65 with ASA physical status I to II scheduled for VATS under general anesthesia.

Not a fit: Patients with ASA physical status III to IV, major spine deformities, or other specified contraindications may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing thoracic surgery.

How similar studies have performed: Previous studies have shown promising results for both nerve block techniques in managing postoperative pain, indicating potential success for this comparative approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients American Society of Anesthesiologists physical status (ASA) I to II
* Both sexes.
* Aged ≥ 20 to ≤ 65years.
* Scheduled for VATS under general anesthesia.

Exclusion Criteria:

* Patient's refusal.
* Patients American Society of Anesthesiologists physical status (ASA) III to IV
* Patients with major spine deformities.
* Disruption of the local anatomy, secondary, for instance, to the presence of chest drains or surgical emphysema, resulting in difficulty in ultrasound interpretation and distortion of tissue planes.
* Patients with bleeding disorders and coagulopathy.
* Infection at the injection site.
* Known allergy to local anesthetics.
* Patients with pre-existing myopathy or neuropathy.
* Ipsilateral diaphragmatic paresis.
* Tumors in the paravertebral space at the level of injection.

Where this trial is running

Cairo, Abbasia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Post Operative Pain, Acuteregional anesthesia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.