Comparing two types of nerve blocks for pain relief after breast surgery

Bilateral Ultrasound-Guided Erector Spinae Plane Block or Serratus Anterior Plane Block For Postoperative Analgesia in Breast Reduction Surgery: A Prospective, Randomized and Controlled Trial

NA · Sisli Hamidiye Etfal Training and Research Hospital · NCT06862752

This study is testing which of two types of nerve blocks can better relieve pain after breast reduction surgery for women aged 18-65.

Quick facts

PhaseNA
Study typeInterventional
Enrollment80 (estimated)
Ages18 Years to 65 Years
SexFemale
SponsorSisli Hamidiye Etfal Training and Research Hospital (other)
Locations1 site (Istanbul)
Trial IDNCT06862752 on ClinicalTrials.gov

What this trial studies

This study aims to compare the effectiveness of the erector spinae plane block and the serratus anterior plane block in managing postoperative pain for patients undergoing breast reduction surgery. By utilizing these regional anesthesia techniques, the study seeks to reduce opioid consumption and its associated side effects, thereby enhancing recovery and patient satisfaction. The trial will involve female patients aged 18-65 who are classified as ASA I-II and are scheduled for elective surgery. The outcomes will focus on the analgesic effects of each block method in the postoperative setting.

Who should consider this trial

Good fit: Ideal candidates for this study are female patients aged 18-65 with ASA physical status I-II who are scheduled for elective breast reduction surgery.

Not a fit: Patients with allergies to local anesthetics, severe obesity, or significant liver or renal deficiencies may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing breast reduction surgery, minimizing opioid use and enhancing recovery.

How similar studies have performed: Other studies have shown promising results with similar regional anesthesia techniques for postoperative pain management, indicating a potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* American Society of Anesthesiologists (ASA) I-II,
* 18-65 years of age, adult,
* female patients
* undergoing elective breast reduction surgery

Exclusion Criteria:

* Allergy to amide-type local anesthetics
* Infection at the block injection site
* Severe obesity (BMI \> 35 kg/m2)
* Liver or renal deficiency
* Patients with anatomical deformities
* Recent use of analgesic drugs
* Patient refusal or inability to consent

Where this trial is running

Istanbul

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Post Operative Pain, Opioid-Related Disorders, post operative pain, opioid consumption, erector spinae block, serratus anterior plane block

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.