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Clinical trial Recruiting at 1 site Interventional Ages 21 to 60

Comparing two types of nerve blocks for pain relief after abdominal surgery

Official title: Is Erector Spinae Plane Block More Effective Than Rectus Sheath Block for Postoperative Analgesia After Supraumbilical Surgery in Adult Patients

Run by Damanhour Teaching Hospital · NCT05179928 · Data updated 2026-11-12

This study is testing which type of nerve block, the erector spinae plane block or the rectus sheath block, works better for pain relief after abdominal surgery to help adults recover with less need for opioids.

More Post Operative Pain trials

Quick facts

Study typeInterventional
Ages21 Years to 60 Years
SexAll
Enrollment60 (estimated)
SponsorDamanhour Teaching Hospital
Government
Locations1 site (Damanhūr, El-Beheira)
StatusRecruiting
StartedAugust 1, 2026
Main results expectedFebruary 15, 2027
Study endsMarch 1, 2027
Registry record updatedSeptember 21, 2026
Trial IDNCT05179928 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 21 to 60 years with an ASA physical status of II or less and a BMI under 35 kg/m².

Probably not a fit

Patients who may not benefit from this study include those with severe comorbidities, altered mental status, or those outside the specified age and BMI criteria.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to compare the effectiveness of the erector spinae plane block (ESPB) and the rectus sheath block (RSB) in providing postoperative pain relief for adult patients undergoing supraumbilical surgery. The focus is on reducing the need for opioids, which can have adverse side effects, by utilizing regional analgesic techniques. The study will evaluate patient outcomes related to pain management and overall recovery following surgery.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies that minimize opioid use after surgery.

How similar studies have gone: Previous studies have indicated that regional analgesic techniques like ESPB and RSB can effectively manage postoperative pain with fewer side effects, suggesting potential success for this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* American Society of Anesthesiologists (ASA) physical status ≤ II
* Age from 21 to 60 years
* Body Mass Index (BMI) \< 35 kg/m²

Exclusion Criteria:

* American Society of Anesthesiologists (ASA) physical status \> II
* Age \< 21 years or \> 60 years
* Body Mass Index (BMI) ≥ 35
* Local infection at the puncture site
* Altered mental status
* Pregnant women
* Allergy to study drugs
* Chronic pain
* Coagulation abnormalities or on anticoagulants
* Severe hepatic or kidney disease

Where it's running

  • Damanhour Teaching Hospital
    Damanhūr, El-Beheira, Egypt     Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Post Operative Pain 71Damanhour Teaching Hospital 5
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.