Clinical trial Recruiting at 1 site Phase 4 Interventional Ages 8 to 18

Comparing two types of nerve blocks for knee surgery in children

Official title: A Pilot Study Comparing Anterior Femoral Cutaneous Nerve Blocks to Adductor Canal Blocks in Pediatric Ambulatory Knee Surgeries

Run by Hospital for Special Surgery, New York · NCT06590402 · Data updated 2026-11-12

This study is testing which type of nerve block works better for pain relief in children aged 8-18 having knee surgery for ligament repairs.

Quick facts

PhasePhase 4
Study typeInterventional
Ages8 Years to 18 Years
SexAll
Enrollment60 (estimated)
SponsorHospital for Special Surgery, New York
Academic / other
Locations1 site (New York, New York)
StatusRecruiting
StartedJune 6, 2025
Main results expectedJune 2027
Study endsJanuary 2028
Registry record updatedOctober 13, 2026
Trial IDNCT06590402 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are children aged 8-18 years who are undergoing ACL or MPFL reconstruction and weigh 40 kg or more.

Probably not a fit

Patients undergoing revision surgery, bilateral surgery, or those with contraindications to the study protocol may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot clinical trial aims to compare the effectiveness of anterior femoral cutaneous nerve block (AFCNB) versus adductor canal block (ACB) in pediatric patients undergoing anterior cruciate ligament (ACL) or medial patellofemoral ligament (MPFL) reconstruction. The study will assess postoperative functional outcomes, opioid requirements, pain intensity levels, sensory deficits, and patient-reported outcomes in children aged 8-18 years. By collecting this data, the researchers hope to inform a larger randomized controlled trial to further investigate these anesthesia techniques.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management and functional recovery for pediatric patients undergoing knee surgeries.

How similar studies have gone: While there is limited literature on this specific comparison, similar studies have explored peripheral nerve blocks in pediatric orthopedic procedures, indicating potential for success.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 8-18 years old at the time of surgery
* Patients 40kg and above
* ACL reconstruction of MPFL reconstruction surgery with participating surgeons

Exclusion Criteria:

* revision surgery
* bilateral surgery
* general anesthesia
* contraindications to any part of the study protocol
* relevant pre-existing neurological deficit
* chronic pain

Where it's running

  • Hospital for Special Surgery
    New York, New York, United States
    Recruiting

Study contacts

  • Principal investigator: Kathryn DelPizzo, MD — Hospital for Special Surgery, New York
  • Study coordinator: Marko Popovic
  • Email: popovicm@hss.edu
  • Phone: 646-797-8948

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.