Comparing two types of nerve blocks for knee surgery in children
Official title: A Pilot Study Comparing Anterior Femoral Cutaneous Nerve Blocks to Adductor Canal Blocks in Pediatric Ambulatory Knee Surgeries
Run by Hospital for Special Surgery, New York · NCT06590402 · Data updated 2026-11-12
This study is testing which type of nerve block works better for pain relief in children aged 8-18 having knee surgery for ligament repairs.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Ages | 8 Years to 18 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Hospital for Special Surgery, New York Academic / other |
| Locations | 1 site (New York, New York) |
| Status | Recruiting |
| Started | June 6, 2025 |
| Main results expected | June 2027 |
| Study ends | January 2028 |
| Registry record updated | October 13, 2026 |
| Trial ID | NCT06590402 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are children aged 8-18 years who are undergoing ACL or MPFL reconstruction and weigh 40 kg or more.
✕Probably not a fit
Patients undergoing revision surgery, bilateral surgery, or those with contraindications to the study protocol may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This pilot clinical trial aims to compare the effectiveness of anterior femoral cutaneous nerve block (AFCNB) versus adductor canal block (ACB) in pediatric patients undergoing anterior cruciate ligament (ACL) or medial patellofemoral ligament (MPFL) reconstruction. The study will assess postoperative functional outcomes, opioid requirements, pain intensity levels, sensory deficits, and patient-reported outcomes in children aged 8-18 years. By collecting this data, the researchers hope to inform a larger randomized controlled trial to further investigate these anesthesia techniques.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management and functional recovery for pediatric patients undergoing knee surgeries.
How similar studies have gone: While there is limited literature on this specific comparison, similar studies have explored peripheral nerve blocks in pediatric orthopedic procedures, indicating potential for success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 8-18 years old at the time of surgery * Patients 40kg and above * ACL reconstruction of MPFL reconstruction surgery with participating surgeons Exclusion Criteria: * revision surgery * bilateral surgery * general anesthesia * contraindications to any part of the study protocol * relevant pre-existing neurological deficit * chronic pain
Where it's running
-
Hospital for Special Surgery
New York, New York, United States Recruiting
Study contacts
- Principal investigator: Kathryn DelPizzo, MD — Hospital for Special Surgery, New York
- Study coordinator: Marko Popovic
- Email: popovicm@hss.edu
- Phone: 646-797-8948
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Analgesic effects of adding BiFeS block to adductor canal block after ACL reconstruction
This study tests whether adding a BiFeS block to the standard adductor canal block provides better pain relief after ACL reconstruction.
-
Donor ankle sensorimotor recovery after ACL reconstruction with a peroneus longus graft
This study tests how the donor ankle recovers sensorimotor function after ACL reconstruction using a peroneus longus tendon autograft in adults 18–55.
-
ACL Tear: Reconstruction vs Primary Repair outcomes after surgery
This study tests how patients who had ACL reconstruction compare with those who had arthroscopic primary ACL repair in terms of strength, endurance, fatigue, knee stability, and function after surgery.
-
Fractal versus steady visual walking cues after ACL reconstruction
This tests whether fractal (variable) visual walking cues or steady metronome-like cues help athletes who had ACL reconstruction walk with steadier, safer patterns.
-
Brain-computer visualization training to improve muscle activation after orthopedic surgery
This tests whether adding EEG-based neurofeedback visualization to usual physical therapy helps adults recovering from ACL, hip, or knee surgery activate their muscles better and speed recovery.
-
Eccentric training for rehabilitation after ACL surgery
This study is testing if a special type of exercise called eccentric training helps people recover better after ACL surgery compared to regular rehab exercises.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.