Comparing two types of intraocular lenses for cataract surgery
Clinical Evaluation of Extended Depth-of-focus Intraocular Lens in Refractive Cataract Surgery
NA · Second Affiliated Hospital, School of Medicine, Zhejiang University · NCT06658119
This study is testing two different types of lenses for cataract surgery to see which one helps people see better after their operation.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Ages | 40 Years to 80 Years |
| Sex | All |
| Sponsor | Second Affiliated Hospital, School of Medicine, Zhejiang University (other) |
| Locations | 1 site (Hangzhou, Zhejiang) |
| Trial ID | NCT06658119 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the outcomes of two different extended depth-of-focus intraocular lenses in patients undergoing cataract surgery. A total of 90 participants will be randomly assigned to receive either the Tecnis Synergy ZFR00 or the Tecnis Symfony ZXR00 lens. The study will assess visual acuity, subjective manifest refraction, and visual quality through follow-up visits up to three months post-surgery. The randomized controlled design ensures a robust comparison between the two lens types.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 40 to 80 with age-related cataracts and minimal preoperative astigmatism.
Not a fit: Patients with significant ocular surface abnormalities or other serious ocular disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance visual outcomes for cataract patients by identifying the superior intraocular lens option.
How similar studies have performed: Previous studies have shown promising results with extended depth-of-focus intraocular lenses, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * age-related cataract patients aged between 40 to 80 * patients with preoperative astigmatism less than 0.75 D, and kappa value less than 0.7 mm * patients who plan to receive femtosecond laser-assisted cataract surgery Exclusion Criteria: * patients with ocular surface abnormalities such as irregular corneal astigmatism, corneal scarring, keratoconus, and pterygium) * patients with history of ocular trauma or surgery * patients with coexisting ocular disorders such as glaucoma, retinal vascular occlusive disease, retinal detachment, diabetic retinopathy, and any optic nerve-related pathologies * patients with concurrent severe systemic diseases * patients who lack of cooperation
Where this trial is running
Hangzhou, Zhejiang
- Eye Center of the Second Affiliated Hospital of Zhejiang University — Hangzhou, Zhejiang, China (RECRUITING)
Study contacts
- Study coordinator: Yueyang Zhong, MD.
- Email: yyzbzhong@zju.edu.cn
- Phone: +8618868125901
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Cataract, cataract surgery, intraocular lens, extended depth-of-focus