Comparing two types of fluids for kidney transplant recovery
The Comparison Between Ringer Lactate Solution and Normal Saline with Dextrose Water in the First Week Post-Operative Period of Deceased Donor and Living Donor Kidney Transplantation
This study is testing whether a special fluid or a different kind of fluid helps kidney transplant patients recover better by looking at their electrolyte levels during the first week after surgery.
Quick facts
| Phase | Phase 3 |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | King Chulalongkorn Memorial Hospital Academic / other |
| Locations | 1 site (Bangkok) |
| Trial ID | NCT06030609 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates the effects of Ringer lactate solution (RLS) versus normal saline solution (NSS) with dextrose water (D5W) on electrolyte balance in kidney transplant recipients during their first week post-surgery. It is a randomized controlled trial involving 60 participants who will be assigned to receive either RLS or NSS with D5W. The primary outcome measured will be serum bicarbonate levels on day 5 after transplantation, while secondary outcomes will include various serum electrolytes and the incidence of delayed graft function.
Who should consider this trial
Good fit: Ideal candidates are adult kidney transplant recipients aged 18 and older at King Chulalongkorn Memorial Hospital.
Not a fit: Patients undergoing multiorgan transplantation or those with known allergies to RLS or NSS may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve electrolyte management and kidney function in post-operative kidney transplant patients.
How similar studies have performed: While similar studies have explored fluid management in kidney transplantation, this specific comparison of RLS and NSS with D5W is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * A kidney transplant recipient who receives transplant at King Chulalongkorn Memorial Hospital. * Age \>=18 years * Both deceased donor and living donor kidney transplantation will be included Exclusion Criteria: * multiorgan transplantation * Known allergy to RLS or NSS
Where this trial is running
Bangkok
- Division of Nephrology, Faculty of Medicine, King Chulalongkorn Memorial Hospital — Bangkok, Thailand (Recruiting)
Study contacts
- Study coordinator: Suwasin Udomkarnjananun, MD, PhD
- Email: suwasin.u@gmail.com
- Phone: +66899679885
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.