Comparing two types of exercises for young people with hemophilia

Comparison of Efficiency of Closed Kinetic Chain Exercises Versus Proprioceptive Exercises in Improving Balance and Gait in Patient With Hemophilia

Not applicable Interventional Bahçeşehir University · NCT05879549

This study tests which type of exercise, closed kinetic chain or proprioceptive, helps young people with hemophilia improve their balance and walking better.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment63 (estimated)
Ages13 Years to 25 Years
SexMale
SponsorBahçeşehir University Academic / other
Locations1 site (Istanbul)
Trial IDNCT05879549 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the effectiveness of closed kinetic chain exercises versus proprioceptive exercises in improving balance, proprioception, and gait in adolescents and young adults with hemophilia. Participants will include individuals diagnosed with Hemophilia A or B, aged 13 to 25, who have experienced lower extremity joint bleeding. The study will measure the differences in outcomes between the two exercise approaches to determine which is more beneficial for this population.

Who should consider this trial

Good fit: Ideal candidates are adolescents and young adults aged 13-25 with Hemophilia A or B and a history of lower extremity joint bleeding.

Not a fit: Patients who have undergone lower extremity surgery in the last 6 months or have a Body Mass Index over 30 kg/m2 may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved exercise recommendations that enhance balance and mobility for young patients with hemophilia.

How similar studies have performed: While there is limited information on similar studies, the approach of comparing different exercise modalities in hemophilia is relatively novel and may provide new insights.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Having been diagnosed with Hemophilia A and Hemophilia B
* Having a blood factor level below 5%,
* Between 13-25 years old
* History of bleeding to the lower extremity and target joint
* Total lower extremity Hemophilia joint health score ≥3
* Using prophylaxis

Exclusion Criteria:

* Having undergone lower extremity surgery in the last 6 months
* Having a Body Mass Index over 30 kg/m2
* Have an inhibitor
* Using a walking aid

Where this trial is running

Istanbul

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Hemophilia AHemophilia Bhemophiliaexercisebalanceproprioception
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.