Comparing two types of enhanced monofocal lenses for cataract surgery

Intermediate Visual Acuity Comparison of Two Non-diffractive Enhanced Monofocal Intraocular Lenses

Not applicable Interventional Vienna Institute for Research in Ocular Surgery · NCT06345820

This study is testing two types of lenses used in cataract surgery to see which one helps people see better and rely less on glasses for everyday tasks.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment35 (estimated)
Ages21 Years to 105 Years
SexAll
SponsorVienna Institute for Research in Ocular Surgery Academic / other
Locations1 site (Vienna)
Trial IDNCT06345820 on ClinicalTrials.gov

What this trial studies

This study compares the clinical performance of two enhanced monofocal intraocular lenses (IOLs) designed for cataract surgery. The aim is to evaluate how these lenses perform in restoring vision and achieving spectacle independence for patients. Participants will undergo bilateral implantation of either the Evolux or Tecnis Eyhance IOLs, with assessments made on visual acuity and patient satisfaction. The study focuses on patients with cataracts who are seeking improved vision without reliance on glasses for intermediate and near tasks.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 21 and older with bilateral cataracts and sufficient visual acuity.

Not a fit: Patients with active ocular diseases or those requiring specific types of IOLs, such as toric lenses for astigmatism, may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide patients with improved vision and reduced dependence on glasses after cataract surgery.

How similar studies have performed: Previous studies have shown promising results with enhanced monofocal IOLs, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Bilateral cataract
* Age 21 or older
* Visual acuity \> 0.05
* Axial length: 22.00-26.00mm
* Normal findings in the medical history and physical examination unless the investigator considers an abnormality to be clinically irrelevant
* Written informed consent prior to surgery
* Availability, willingness and sufficient cognitive awareness to comply with examination procedures

Exclusion Criteria:

* Active ocular disease (e.g. chronic uveitis, proliferative diabetic retinopathy, chronic glaucoma not responsive to medication)
* Relevant other ophthalmic diseases such as pseudoexfoliation syndrome (PEX), Intraoperative Floppy Iris Syndrome (IFIS)
* Corneal decompensation or corneal endothelial cell insufficiency
* Amblyopia
* Previous ocular surgery or trauma
* Persons who are pregnant or nursing (pregnancy test will be taken in women of reproductive age)
* Astigmatism with the need for a toric IOL

Where this trial is running

Vienna

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions CataractCataract surgeryIntraocular lens
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.