Comparing two topical anesthetics for pain relief during dermatological procedures
Comparison of Compounded Topical Anesthetics for Pain Relief of Intense Pulsed Light, Pulse Dye Laser, and Microneedling Treatments
This study is testing whether a new combination cream for numbing can help people feel less pain during certain skin treatments compared to a regular numbing cream.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Dartmouth-Hitchcock Medical Center Academic / other |
| Locations | 1 site (Lebanon, New Hampshire) |
| Trial ID | NCT06569537 on ClinicalTrials.gov |
What this trial studies
This pilot study aims to evaluate the effectiveness of a compounded topical anesthetic containing Benzocaine, Lidocaine, and Tetracaine (BLT) compared to a standard 4% Lidocaine topical anesthetic. The study focuses on patients undergoing Intense Pulse Light (IPL), Pulse Dye Laser (PDL), and microneedling procedures to assess pain relief. Participants will be monitored for pain levels during these dermatological treatments to determine which anesthetic provides better relief.
Who should consider this trial
Good fit: Ideal candidates are men and women aged 18 to 75 with scheduled dermatology appointments for IPL, PDL, or microneedling.
Not a fit: Patients with allergies to the study anesthetics, certain medical conditions, or those who are pregnant or breastfeeding may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management options for patients undergoing dermatological procedures.
How similar studies have performed: While this study explores a specific compounded anesthetic, similar approaches have shown promise in improving pain management in dermatological procedures.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Men and women over 18, but not more than 75 years of age. * Patients who have a regularly scheduled dermatology appointment for Intense Pulse Light (IPL), Pulse Dye Laser (PDL), or microneedling. Exclusion Criteria: * Any subject who has a previous history of allergy, sensitivity, and contraindication to benzocaine, lidocaine, or tetracaine. * Patients with cardiac/respiratory disease, seizure disorder, or neuropathies. * Patients who are under treatment for a dermatologic condition that may interfere with the evaluation of the study. * Pregnant women and women who are breastfeeding. * Patients who report concurrent use of anxiolytics or opiates, which may interfere with the interpretation of results.
Where this trial is running
Lebanon, New Hampshire
- Dartmouth Hitchcock Dermatology Clinic — Lebanon, New Hampshire, United States (Recruiting)
Study contacts
- Principal investigator: Brian J Simmons, MD — Dartmouth Health
- Study coordinator: Nardin Awad, DO
- Email: nardin.awad@hitchcock.org
- Phone: 6036532209
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.