Comparing two therapies for people with OCD

Comparing Exposure v Imagery Rescripting in People With Obsessive Compulsive Disorder (OCD): a Single Case Experimental Design (SCED)

Not applicable Interventional King's College London · NCT06944366

This study is testing whether imagery rescripting or exposure therapy works better to help people with OCD who have troubling thoughts and images feel better in their daily lives.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment10 (estimated)
Ages18 Years and up
SexAll
SponsorKing's College London Academic / other
Locations1 site (London)
Trial IDNCT06944366 on ClinicalTrials.gov

What this trial studies

This project investigates the effectiveness of two therapeutic approaches, imagery rescripting and exposure therapy, for individuals suffering from obsessive-compulsive disorder (OCD) who experience distressing future-oriented thoughts and images. Participants will be assessed for their suitability based on specific criteria, including the presence of ego-dystonic images. The study aims to determine which intervention may provide better relief from symptoms and improve overall functioning in daily life.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and over with a primary diagnosis of OCD who experience distressing future-oriented images.

Not a fit: Patients with psychosis, bipolar disorder, or those currently engaged in other psychotherapy may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to more effective treatment options for individuals with OCD, enhancing their quality of life.

How similar studies have performed: While there is existing research on both imagery rescripting and exposure therapy, this specific comparison in the context of OCD is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18 years or over
* Main diagnosis of OCD (assessed by the Structured Clinical Interview for ICD11)
* Must report future orientated images that are distressing and ego-dystonic

Exclusion Criteria:

* Psychosis, bipolar disorder, or trauma disorder
* Current stimulant or hallucinogenic misuse, alcohol or substance misuse or dependence
* Intellectual disability, dementia, serious cognitive impairment, or organic brain disorder
* Personality Disorder as the main problem
* Active suicidality
* Concurrent engagement in other psychotherapy
* A patient may be taking anti-depressant medication so long as the dose has been stable for 6 weeks and there is no plan to increase the dose.

Where this trial is running

London

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Obsessive-Compulsive Disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.