Comparing two therapies for improving balance and gait in diabetic neuropathy

Comparative Effects of Propioceptive Neuromascular Facilitation and Neural Flossing on Balance and Gait in Diabetic Peripheral Neuropathy

Not applicable Interventional Riphah International University · NCT06397209

This study is testing whether Proprioceptive Neuromuscular Facilitation or Neural Flossing can better improve balance and walking in people aged 45 to 65 with diabetic neuropathy.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment50 (estimated)
Ages45 Years to 65 Years
SexAll
SponsorRiphah International University Academic / other
Locations1 site (Burewala, Punjab)
Trial IDNCT06397209 on ClinicalTrials.gov

What this trial studies

This study aims to compare the effects of Proprioceptive Neuromuscular Facilitation (PNF) and Neural Flossing on balance and gait in individuals diagnosed with diabetic peripheral neuropathy. Participants aged 45 to 65 with type I or II diabetes will be assessed using the Michigan Neuropathy Screening Instrument to ensure they meet eligibility criteria. The study seeks to determine which of the two interventions is more effective in enhancing balance and reducing fall risk among patients. This head-to-head comparison is essential as previous studies have not directly evaluated these two methods against each other.

Who should consider this trial

Good fit: Ideal candidates are individuals aged 45 to 65 with type I or II diabetes who have been clinically diagnosed with diabetic peripheral neuropathy.

Not a fit: Patients with other neurological or orthopedic impairments, major vascular complications, severe retinopathy, or severe nephropathy may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a more effective therapeutic approach to improve balance and reduce fall risk in patients with diabetic neuropathy.

How similar studies have performed: While both PNF and Neural Flossing have been studied independently, this is the first comprehensive study comparing their effects directly, making it a novel approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Clinically Diagnosed with type I and II diabetes
* Patients 45 to 65 years of age
* The participants who scored \<3 as per the Michigan Neuropathy Screening Instrument (MNSI) were included in the study.
* Able to stand and walk without assistance

Exclusion Criteria:

* Patients have other neurological or orthopedic impairments (such as stroke,cerebral palsy, poliomyelitis, rheumatoid arthritis, prosthesis, or moderate or severe osteoarthritis)
* Major vascular complications (venous or arterial ulcers).
* Severe retinopathy
* Severe nephropathy that causes edema or requires haemodialysis

Where this trial is running

Burewala, Punjab

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Diabetic Peripheral NeuropathyMichigan Neuropathy Screening InstrumentNeural FlossingPropioceptive Neuromascular facilitation
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.