Clinical trial Recruiting at 1 site Interventional Ages 18 to 75

Comparing two surgical methods for treating right colon cancer

Official title: A Prospective, Randomized, Open, Parallel-controlled, Superiority Clinical Study of Radical Right Hemicolectomy Versus Radical Right Hemicolectomy Combined with Indocyanine Green Fluorescence Imaging Lymphatic Tracer Dissection for the Treatment of Right Colon Cancer

Run by Sun Yat-sen University · NCT06485609 · Data updated 2026-11-12

This study tests whether using special imaging during surgery helps people with right colon cancer recover better than just having the standard surgery alone.

Quick facts

Study typeInterventional
Ages18 Years to 75 Years
SexAll
Enrollment1200 (estimated)
SponsorSun Yat-sen University
Academic / other
Drugs / interventionschemotherapy, radiation
Locations1 site (Guangzhou)
StatusRecruiting
StartedAugust 10, 2024
Main results expectedJune 1, 2027
Study endsJuly 1, 2031
Registry record updatedJanuary 17, 2025
Trial IDNCT06485609 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 to 75 with confirmed adenocarcinoma of the right colon at specific stages (T1-T4a N+ M0).

Probably not a fit

Patients with multiple primary colon cancers, those requiring emergency surgery, or who are unsuitable for laparoscopic procedures may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the outcomes of radical right hemicolectomy alone versus a combined approach using indocyanine green fluorescence imaging for lymphatic tracer dissection in patients with right colon cancer. The study aims to determine if the addition of fluorescence imaging improves surgical results and patient recovery. Participants will undergo laparoscopic surgery, and their clinical outcomes will be monitored and compared. The trial focuses on patients with confirmed adenocarcinoma located in the right colon.

Why it matters

Potential benefit: If successful, this approach could lead to improved surgical outcomes and recovery for patients with right colon cancer.

How similar studies have gone: While the use of indocyanine green fluorescence imaging is gaining traction, this specific combination approach is relatively novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 1\. Age between 18 and 75 years old 2. Confirmed adenocarcinoma cancer pathologically 3. Location of tumor: from the cecum to the right third of the transverse colon 4. CT showed right colon cancer: T1-T4a N+ M0 5. ASA scores I-III 6. ECOG (Eastern Cooperative Oncology Group) scale performance status of 0 or 1 7. Patient or family member, able to understand the study protocol and willing to participate in the study, providing written informed consent

Exclusion Criteria:

* 1\. Simultaneous or heterochronic multiple primary colon cancer 2. Patients with intestinal obstruction, intestinal perforation, intestinal bleeding, etc. requiring emergency surgery 3. Unsuitable for laparoscopic surgery (e.g., extensive adhesions due to previous major abdominal surgery; unsuitable for pneumoperitoneum for various reasons, etc.) 4. Pregnant or lactating women 5. Have a history of serious mental illness 6. History of iodine allergy 7. History of other malignant diseases within the last five years 8. History of prior neoadjuvant chemotherapy or radiation therapy 9. History of unstable angina or myocardial infarction within the last 6 months 10. History of continuous systemic corticosteroid use within one month

Where it's running

  • The Sixth Affiliated Hospital, Sun Yat-sen University
    Guangzhou, China
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.