Comparing two surgical methods for treating open-angle glaucoma
Longterm Comparison of Gonioscopy-assisted Transluminal Trabeculotomy and Canaloplasty in Open-angle Glaucoma Treatment
NA · Medical University of Bialystok · NCT05366647
This study is testing which of two surgical methods, Gonioscopy-assisted Transluminal Trabeculotomy or canaloplasty, works better and is safer for people with open-angle glaucoma that isn't controlled by medication.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Medical University of Bialystok (other) |
| Locations | 1 site (Bialystok) |
| Trial ID | NCT05366647 on ClinicalTrials.gov |
What this trial studies
This study compares the effectiveness and safety of Gonioscopy-assisted Transluminal Trabeculotomy and canaloplasty in patients with medically uncontrolled open-angle glaucoma. Both procedures aim to improve aqueous outflow but utilize different techniques, with canaloplasty being a newer approach. The study will evaluate success rates, intraocular pressure, medication burden, and complication rates between the two surgical methods. This is the first study to directly compare these two procedures.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older with confirmed uncontrolled open-angle glaucoma and no prior glaucoma surgery.
Not a fit: Patients with angle closure glaucoma, congenital glaucoma, or inflammatory glaucoma may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could help identify the more effective surgical option for patients with open-angle glaucoma, potentially improving their treatment outcomes.
How similar studies have performed: There have been no prior studies comparing Gonioscopy-assisted Transluminal Trabeculotomy and canaloplasty, making this approach novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 Years and older (Adult, Older Adult) * patients with confirmed uncontrolled open angle glaucoma * no prior glaucoma surgery (once laser trabeculoplasty or cyclophotocoagulation) allowed Exclusion Criteria: * angle closure glaucoma * congenital glaucoma * inflammatory glaucoma
Where this trial is running
Bialystok
- Ophthalmology Clinic Medical University of Bialystok — Bialystok, Poland (RECRUITING)
Study contacts
- Principal investigator: Joanna Konopińska — Medical University of Bialystok, Poland
- Study coordinator: Joanna Konopińska
- Email: joannakonopinska@o2.pl
- Phone: +48600471666
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Glaucoma, Open-Angle, Gonioscopy-assisted Transluminal Trabeculotomy, Canaloplasty, Glaucoma