Comparing two surgical methods for ovarian cancer treatment
Official title: Comparison of Rectosigmoid Resection and Seromuscular Tumor Shaving Methods in Ovarian Cancer Surgery (BROSEOC)
Run by Cukurova University · NCT04665635 · Data updated 2026-11-12
This study tests which surgical method, either removing part of the rectum or just shaving the tumor, works better for people with advanced ovarian cancer that has spread to that area.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 120 (estimated) |
| Sponsor | Cukurova University Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 2 sites (Adana and 1 other locations) |
| Status | Recruiting |
| Started | March 1, 2021 |
| Main results expected | January 2025 |
| Study ends | December 2026 |
| Registry record updated | August 29, 2024 |
| Trial ID | NCT04665635 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients with epithelial ovarian cancer and confirmed serosal or seromuscular rectosigmoid infiltration who meet specific health criteria.
✕Probably not a fit
Patients with nonepithelial ovarian cancers or those requiring extensive bowel resections may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial evaluates the effectiveness of rectosigmoid resection versus seromuscular tumor shaving in patients with epithelial ovarian cancer that has metastasized to the rectosigmoid area. The study aims to determine which surgical approach leads to better outcomes in terms of complete tumor removal and overall patient survival. Participants will undergo one of the two surgical interventions, and their recovery and recurrence rates will be monitored. The trial is crucial as it addresses a common complication in advanced ovarian cancer treatment.
Why it matters
Potential benefit: If successful, this study could improve surgical outcomes and survival rates for patients with advanced ovarian cancer.
How similar studies have gone: While there have been studies on surgical interventions for ovarian cancer, this specific comparison of techniques is novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Epithelial ovarian cancer * Negative colonoscopy ( no mucosal involvement) * Intraoperative confirmed serosal or seromuscular rectosigmoid infiltration * ECOG \<3 * ASA \<3 Exclusion Criteria: * Nonepithelial ovarian cancers * Rectosigmoid mucosal infiltration * Total or subtotal colectomy necessitating large bowel infiltrations * ECOG \>2 * ASA \>2
Where it's running
-
Cukurova University
Adana, Turkey (Türkiye) Recruiting -
Cukurova University
Adana, Turkey (Türkiye) Not yet recruiting
Study contacts
- Study coordinator: Ghanim Khatib, MD
- Email: ghanim.khatib@gmail.com
- Phone: +903223386060
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.