Clinical trial Recruiting at 1 site Interventional Ages 18 and up Women only

Comparing two surgical methods for ovarian cancer treatment

Official title: Comparison of Rectosigmoid Resection and Seromuscular Tumor Shaving Methods in Ovarian Cancer Surgery (BROSEOC)

Run by Cukurova University · NCT04665635 · Data updated 2026-11-12

This study tests which surgical method, either removing part of the rectum or just shaving the tumor, works better for people with advanced ovarian cancer that has spread to that area.

Quick facts

Study typeInterventional
Ages18 Years and up
SexWomen only
Enrollment120 (estimated)
SponsorCukurova University
Academic / other
Drugs / interventionschemotherapy
Locations2 sites (Adana and 1 other locations)
StatusRecruiting
StartedMarch 1, 2021
Main results expectedJanuary 2025
Study endsDecember 2026
Registry record updatedAugust 29, 2024
Trial IDNCT04665635 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include patients with epithelial ovarian cancer and confirmed serosal or seromuscular rectosigmoid infiltration who meet specific health criteria.

Probably not a fit

Patients with nonepithelial ovarian cancers or those requiring extensive bowel resections may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of rectosigmoid resection versus seromuscular tumor shaving in patients with epithelial ovarian cancer that has metastasized to the rectosigmoid area. The study aims to determine which surgical approach leads to better outcomes in terms of complete tumor removal and overall patient survival. Participants will undergo one of the two surgical interventions, and their recovery and recurrence rates will be monitored. The trial is crucial as it addresses a common complication in advanced ovarian cancer treatment.

Why it matters

Potential benefit: If successful, this study could improve surgical outcomes and survival rates for patients with advanced ovarian cancer.

How similar studies have gone: While there have been studies on surgical interventions for ovarian cancer, this specific comparison of techniques is novel and has not been extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Epithelial ovarian cancer
* Negative colonoscopy ( no mucosal involvement)
* Intraoperative confirmed serosal or seromuscular rectosigmoid infiltration
* ECOG \<3
* ASA \<3

Exclusion Criteria:

* Nonepithelial ovarian cancers
* Rectosigmoid mucosal infiltration
* Total or subtotal colectomy necessitating large bowel infiltrations
* ECOG \>2
* ASA \>2

Where it's running

  • Cukurova University
    Adana, Turkey (Türkiye)
    Recruiting
  • Cukurova University
    Adana, Turkey (Türkiye)
    Not yet recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.