Comparing two self-management programs for serious mental illness

Comparative Effectiveness of Integrated Illness Management and Recovery Versus the Chronic Disease Self-Management Program

Not applicable Interventional Dartmouth-Hitchcock Medical Center · NCT03966872

This study is testing which of two self-management programs helps people with serious mental illness better manage their health, focusing on either both mental and physical health or just physical health.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment600 (estimated)
Ages18 Years and up
SexAll
SponsorDartmouth-Hitchcock Medical Center Academic / other
Locations2 sites (Louisville, Kentucky and 1 other locations)
Trial IDNCT03966872 on ClinicalTrials.gov

What this trial studies

This study will enroll 600 individuals with serious mental illness receiving services at Centerstone in Kentucky or Tennessee. It aims to compare two evidence-based self-management interventions: Integrated Illness Management and Recovery (I-IMR), which focuses on both physical and mental health, and the Stanford Chronic Disease Self-Management Program (CDSMP), which primarily addresses physical health. Participants will be randomly assigned to either I-IMR or CDSMP, with the goal of assessing the effectiveness of these programs in managing their conditions. The study is designed to provide insights into which intervention may be more beneficial for this population.

Who should consider this trial

Good fit: Ideal candidates are individuals diagnosed with serious mental illness and a chronic medical condition, receiving services at Centerstone in Kentucky or Tennessee.

Not a fit: Patients who do not have a serious mental illness or those with well-controlled medical conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve self-management strategies for patients with serious mental illness, enhancing their overall health outcomes.

How similar studies have performed: Previous studies have shown success with similar self-management interventions, but this specific comparison of I-IMR and CDSMP is novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Serious Mental Illness (diagnosis of schizophrenia, schizoaffective disorder, bipolar disorder, or chronic depression with moderate impairment in functioning) receiving services at Centerstone(KY and TN)
* Diagnosis of a chronic medical condition increasing risk of early mortality from cardiovascular or respiratory disease (e.g., diabetes, hyperlipidemia, hypertension, COPD, heart failure, tobacco dependence, obesity), and at least 1 ER visit or hospitalization within the past year or judgment by the treatment team of substantial need for illness self-management training.

Exclusion Criteria:

* Consumers who do not speak English
* Consumers with either no, or a well-controlled medical condition will not be included
* Individuals residing in a nursing home or other institution
* Evidence of significant cognitive impairment as indicated by a Mini Mental Status Examination score \<24, will be excluded

Eligibility for the COVID -related substudy is dependent on enrollment and participation in the parent project.

Where this trial is running

Louisville, Kentucky and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Mental IllnessChronic Diseaseintegrated healthmental healthillness managementcardiovascular diseasephysical health
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.