Comparing two pain relief methods for thoracic surgery

Analgesic Efficacy of Mid-point Transverse Process to Pleura Block Compared With Thoracic Paravertebral Block in Adult Patients Undergoing Posterolateral Thoracotomy Incisions: A Randomized Controlled Study

NA · Fayoum University Hospital · NCT06361121

This study is testing which pain relief method works better for patients having thoracic surgery: a new type of nerve block or a standard one.

Quick facts

PhaseNA
Study typeInterventional
Enrollment180 (estimated)
Ages18 Years and up
SexAll
SponsorFayoum University Hospital (other)
Locations1 site (Fayoum)
Trial IDNCT06361121 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to compare the effectiveness of the mid-point transverse process to pleura (MTP) block versus the thoracic paravertebral (TPV) block in providing pain relief for patients undergoing elective thoracic surgeries via posterolateral thoracotomy. Patients will be randomly assigned to one of the two groups, and both the surgical and anesthesia teams will be blinded to the group assignments to ensure unbiased results. The study will monitor patients' vital signs and pain levels to evaluate the efficacy of each anesthetic technique.

Who should consider this trial

Good fit: Ideal candidates include patients scheduled for elective thoracic surgeries such as pneumectomy, lobectomy, bullectomy, or pleural decortication.

Not a fit: Patients with significant renal, hepatic, or cardiovascular diseases, or those with contraindications to regional anesthesia will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management techniques for patients undergoing thoracic surgery.

How similar studies have performed: Previous studies have shown that the MTP block provides effective analgesia in various surgical procedures, indicating potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients Scheduled for elective thoracic surgery for pneumectomy, lobectomy, bullectomy or pleural decortication via posterolateral thoracotomy incision.
* American Society of Anesthesiologists (ASA) physical status I-III patients

Exclusion Criteria:

* Patient refusal.
* Significant renal, hepatic and cardiovascular diseases.
* History of allergy to one of the study drugs.
* Any contraindication to regional anesthesia such as local infection or bleeding disorders.
* Chronic opioid use, history of chronic pain and cognitive disorders.
* Emergent or re-do surgeries

Where this trial is running

Fayoum

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Bronchiectasis, Lung Neoplasm, Emphysematous Bleb of Lung, Mid-point Transverse Process to Pleura Block, Posterolateral Thoracotomy Incisions

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.