Comparing two pain relief methods after gallbladder surgery
Official title: Ultrasound Guided External Oblique Intercostal (EOI) Block Versus Erector Spinae Plane Block (ESPB) for Postoperative Analgesia in Laparoscopic Cholecystectomy
Run by Assiut University · NCT05272280 · Data updated 2026-11-12
This study is testing two different pain relief methods after gallbladder surgery to see which one helps patients feel better with less pain.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Assiut University Academic / other |
| Locations | 1 site (Asyut, Assiut, Asyut Governorate, Egypt,) |
| Status | Recruiting |
| Started | May 1, 2022 |
| Main results expected | January 2028 |
| Study ends | March 2028 |
| Registry record updated | November 3, 2026 |
| Trial ID | NCT05272280 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 to 65 with a BMI of 18-35, classified as ASA physical status I or II, and scheduled for elective laparoscopic cholecystectomy.
✕Probably not a fit
Patients with allergies to local anesthetics, infections at the injection site, coagulopathy, chronic pain syndromes, or those on prolonged opioid medication may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to compare the effectiveness of two ultrasound-guided pain relief techniques, the External oblique intercostal (EOI) block and the Erector spinae plane block (ESPB), for managing postoperative pain in patients undergoing laparoscopic cholecystectomy. The hypothesis is that both techniques will provide effective analgesia following the surgery. Participants will be monitored for pain relief and any potential side effects associated with each method.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing laparoscopic cholecystectomy.
How similar studies have gone: Other studies have shown promising results with similar ultrasound-guided analgesic techniques, suggesting potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age between 18 and 65 years with a body mass index (BMI) of 18-35 kg/m2, * patients with the American Society of Anesthesiologists (ASA) physical status I/II, * Patients scheduled for elective laparoscopic cholecystectomy. Exclusion Criteria: * Allergy to local anaesthetics, * Infection at the site of injection, * Coagulopathy, * Chronic pain syndromes, * Prolonged opioid medication, * Patients who received any analgesic 24 h before surgery.
Where it's running
-
Assiut University hospital
Asyut, Assiut, Asyut Governorate, Egypt,, Egypt Recruiting
Study contacts
- Study coordinator: Magdy M mahdy, MD
- Email: magdymahdy84@yahoo.com
- Phone: 0109 650 2058
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.