Clinical trial Recruiting at 1 site Interventional Ages 18 to 65

Comparing two pain relief methods after gallbladder surgery

Official title: Ultrasound Guided External Oblique Intercostal (EOI) Block Versus Erector Spinae Plane Block (ESPB) for Postoperative Analgesia in Laparoscopic Cholecystectomy

Run by Assiut University · NCT05272280 · Data updated 2026-11-12

This study is testing two different pain relief methods after gallbladder surgery to see which one helps patients feel better with less pain.

Quick facts

Study typeInterventional
Ages18 Years to 65 Years
SexAll
Enrollment50 (estimated)
SponsorAssiut University
Academic / other
Locations1 site (Asyut, Assiut, Asyut Governorate, Egypt,)
StatusRecruiting
StartedMay 1, 2022
Main results expectedJanuary 2028
Study endsMarch 2028
Registry record updatedNovember 3, 2026
Trial IDNCT05272280 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 to 65 with a BMI of 18-35, classified as ASA physical status I or II, and scheduled for elective laparoscopic cholecystectomy.

Probably not a fit

Patients with allergies to local anesthetics, infections at the injection site, coagulopathy, chronic pain syndromes, or those on prolonged opioid medication may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to compare the effectiveness of two ultrasound-guided pain relief techniques, the External oblique intercostal (EOI) block and the Erector spinae plane block (ESPB), for managing postoperative pain in patients undergoing laparoscopic cholecystectomy. The hypothesis is that both techniques will provide effective analgesia following the surgery. Participants will be monitored for pain relief and any potential side effects associated with each method.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing laparoscopic cholecystectomy.

How similar studies have gone: Other studies have shown promising results with similar ultrasound-guided analgesic techniques, suggesting potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age between 18 and 65 years with a body mass index (BMI) of 18-35 kg/m2,
* patients with the American Society of Anesthesiologists (ASA) physical status I/II,
* Patients scheduled for elective laparoscopic cholecystectomy.

Exclusion Criteria:

* Allergy to local anaesthetics,
* Infection at the site of injection,
* Coagulopathy,
* Chronic pain syndromes,
* Prolonged opioid medication,
* Patients who received any analgesic 24 h before surgery.

Where it's running

  • Assiut University hospital
    Asyut, Assiut, Asyut Governorate, Egypt,, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.