Comparing two pain management techniques after breast surgery

A Comparative Study of Erector Spinae Plane Block and Serratus Posterior Superior Intercostal Plane Block on Postoperative Opioid Consumption Following Breast and Axillary Dissection Surgery: A Randomized Controlled Trial

NA · Medipol University · NCT06833697

This study is testing two different pain relief methods after breast surgery to see which one helps patients feel better while using fewer opioids.

Quick facts

PhaseNA
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years to 80 Years
SexAll
SponsorMedipol University (other)
Locations1 site (Istanbul)
Trial IDNCT06833697 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of two ultrasound-guided nerve blocks, the erector spinae plane block (ESPB) and the serratus posterior superior intercostal plane block (SPSIP), in reducing postoperative opioid consumption following breast surgery. It aims to determine which technique provides better pain relief while minimizing opioid-related side effects such as nausea and respiratory depression. The study will be conducted as a prospective, randomized controlled trial at Medipol Mega University Hospital, involving patients aged 18-80 scheduled for breast surgery with axillary lymph node dissection.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18-80 who are scheduled for breast surgery with axillary lymph node dissection and classified as ASA physical status I-III.

Not a fit: Patients with a history of allergies to local anesthetics, pregnant women, or those with psychiatric or neurological disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies that reduce opioid use and enhance recovery for patients undergoing breast surgery.

How similar studies have performed: While both nerve blocks have been used effectively for pain management, this study is novel in directly comparing their efficacy in reducing opioid consumption after breast surgery.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* aged 18-80 years
* Classified as ASA (American Society of Anesthesiologists) physical status I-III
* Scheduled for breast surgery with axillary lymph node dissection

Exclusion Criteria:

* Patients with a history of allergies
* allergic to local anesthetics
* pregnant women
* psychiatric or neurological disorders

Where this trial is running

Istanbul

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Breast Surgery, Erector Spinae Plane Block, Serratus Posterior Superior Intercostal Plane Block, Breast surgery, Postoperative pain, Erector spinae plane block, Opioid consumption, Ultrasound-guided nerve block

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.