Comparing two nerve blocks for pain after laparoscopic gallbladder removal.
Official title: Comparison of Postoperative Analgesic Efficacy of Transversus Abdominis Plane Block (TAP) and Modified Thoracoabdominal Nerve Block (M-TAPA) in Patients Undergoing Laparoscopic Cholecystectomy
Run by Ankara Etlik City Hospital · NCT06932835 · Data updated 2026-11-12
This compares two nerve-block techniques to see which gives better pain relief after laparoscopic gallbladder removal for adults aged 18-65.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | Ankara Etlik City Hospital Government |
| Locations | 1 site (Yenimahalle, Ankara) |
| Status | Recruiting |
| Started | June 2, 2025 |
| Main results expected | April 11, 2026 |
| Study ends | April 21, 2026 |
| Registry record updated | June 4, 2025 |
| Trial ID | NCT06932835 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18-65 years old with ASA physical status I-III, BMI 18-30 kg/m2, scheduled for elective laparoscopic cholecystectomy at the study center and without contraindications to regional anesthesia are ideal candidates.
✕Probably not a fit
Patients outside the age or BMI limits, those with ASA IV or higher, chronic opioid users, emergency surgery patients, pregnant people, those with infection at the injection site, or people allergic to local anesthetics are not likely to benefit or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults scheduled for elective laparoscopic cholecystectomy at Ankara Etlik City Hospital will receive either a transversus abdominis plane (TAP) block or a modified thoracoabdominal (M-TAPA) nerve block as part of multimodal analgesia. Pain scores, opioid consumption, and common side effects such as nausea and respiratory issues will be recorded in the immediate postoperative period. Blocks are administered by anesthesiologists around the time of surgery and patients are followed through early recovery. Outcomes will compare postoperative pain control and opioid-sparing effects between the two techniques.
Why it matters
Potential benefit: If one block works better, patients could have less postoperative pain and need fewer opioids, reducing side effects like nausea and respiratory depression.
How similar studies have gone: Regional abdominal nerve blocks such as TAP have been shown to reduce postoperative pain and opioid use in other studies, while M-TAPA is a newer variation with limited but promising early data.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 to 65 years old * American Society of Anesthesiologists (ASA) physical status I-II-III * Body mass index 18 to 30 kg/m2 * Elective laparoscopic cholecystectomy surgery Exclusion Criteria: * Under 18 and over 65 * ASA score IV and above * Advanced co-morbidity * History of bleeding diathesis * Patient refusing the procedure * Chronic opioid or analgesic use * Patients who will operate under emergency conditions * Block injection site infection * Known allergy to local anesthetics * Pregnancy
Where it's running
-
Ankara Etlik City Hospital
Yenimahalle, Ankara, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Mürüvvet Taşkir Turan, Md
- Email: taskirmuruvvet@gmail.com
- Phone: 00905065536934
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.