Comparing two nerve blocks for pain after laparoscopic gallbladder removal.
Comparison of Postoperative Analgesic Efficacy of Transversus Abdominis Plane Block (TAP) and Modified Thoracoabdominal Nerve Block (M-TAPA) in Patients Undergoing Laparoscopic Cholecystectomy
This compares two nerve-block techniques to see which gives better pain relief after laparoscopic gallbladder removal for adults aged 18-65.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Ankara Etlik City Hospital Government |
| Locations | 1 site (Yenimahalle, Ankara) |
| Trial ID | NCT06932835 on ClinicalTrials.gov |
What this trial studies
Adults scheduled for elective laparoscopic cholecystectomy at Ankara Etlik City Hospital will receive either a transversus abdominis plane (TAP) block or a modified thoracoabdominal (M-TAPA) nerve block as part of multimodal analgesia. Pain scores, opioid consumption, and common side effects such as nausea and respiratory issues will be recorded in the immediate postoperative period. Blocks are administered by anesthesiologists around the time of surgery and patients are followed through early recovery. Outcomes will compare postoperative pain control and opioid-sparing effects between the two techniques.
Who should consider this trial
Good fit: Adults 18-65 years old with ASA physical status I-III, BMI 18-30 kg/m2, scheduled for elective laparoscopic cholecystectomy at the study center and without contraindications to regional anesthesia are ideal candidates.
Not a fit: Patients outside the age or BMI limits, those with ASA IV or higher, chronic opioid users, emergency surgery patients, pregnant people, those with infection at the injection site, or people allergic to local anesthetics are not likely to benefit or be eligible.
Why it matters
Potential benefit: If one block works better, patients could have less postoperative pain and need fewer opioids, reducing side effects like nausea and respiratory depression.
How similar studies have performed: Regional abdominal nerve blocks such as TAP have been shown to reduce postoperative pain and opioid use in other studies, while M-TAPA is a newer variation with limited but promising early data.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 to 65 years old * American Society of Anesthesiologists (ASA) physical status I-II-III * Body mass index 18 to 30 kg/m2 * Elective laparoscopic cholecystectomy surgery Exclusion Criteria: * Under 18 and over 65 * ASA score IV and above * Advanced co-morbidity * History of bleeding diathesis * Patient refusing the procedure * Chronic opioid or analgesic use * Patients who will operate under emergency conditions * Block injection site infection * Known allergy to local anesthetics * Pregnancy
Where this trial is running
Yenimahalle, Ankara
- Ankara Etlik City Hospital — Yenimahalle, Ankara, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: Mürüvvet Taşkir Turan, Md
- Email: taskirmuruvvet@gmail.com
- Phone: 00905065536934
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.