Comparing two methods to reduce opioid use after weight loss surgery
Comparison of Laparoscopic Guided Peri-wound Transversus Abdominis Plane Block With Bupivacaine Versus Local Wound Infiltration on Post-op Opioid Use in Laparoscopic Sleeve Gastrectomy, A Prospective Randomized Controlled Study
This study is testing two different ways to manage pain after weight loss surgery to see which one helps people use fewer opioids.
Quick facts
| Phase | Phase2; Phase3 |
|---|---|
| Study type | Interventional |
| Enrollment | 98 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | Khon Kaen University Academic / other |
| Locations | 1 site (Khon Kaen, Northeastern) |
| Trial ID | NCT05930184 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to compare the effectiveness of laparoscopic guided peri-wound Transversus Abdominis Plane Block with bupivacaine against local wound infiltration in reducing postoperative opioid use following laparoscopic sleeve gastrectomy. Participants will be randomly assigned to one of the two intervention groups to assess which method better alleviates pain and minimizes the need for opioids after surgery. The study is conducted at Srinagarind Hospital in Khon Kaen, Thailand, following established Thai guidelines for patient eligibility.
Who should consider this trial
Good fit: Ideal candidates for this study are patients scheduled to undergo laparoscopic sleeve gastrectomy at Srinagarind Hospital who meet the inclusion criteria.
Not a fit: Patients who are allergic to or contraindicated for bupivacaine, morphine, fentanyl, NSAIDs, or Nefopam, as well as those unable to communicate their pain levels, will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly reduce opioid consumption in patients undergoing laparoscopic sleeve gastrectomy, leading to improved recovery and reduced risk of opioid-related side effects.
How similar studies have performed: Other studies have shown promise in using regional anesthesia techniques like the Transversus Abdominis Plane Block for pain management, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * patient undergoing LSG at Sringarind hospital as indicated by Thai guideline Exclusion Criteria: * Allergic/contraindicated to bupivacaine, morphine, fentanyl, NSAIDs or Nefopam * Unable to describe pain score Opioid addict * denied consent
Where this trial is running
Khon Kaen, Northeastern
- Srinagarind hospital — Khon Kaen, Northeastern, Thailand (Recruiting)
Study contacts
- Principal investigator: Thanatat Panitphong, Doctor of Medicine — Khon Kaen University
- Study coordinator: Thanatat Panitphong, Doctor of Medicine
- Email: thanatat.panitphong@gmail.com
- Phone: +66888868621
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.