Comparing two methods of sperm preparation for intrauterine insemination

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial is a randomized controlled trial that compares two sperm preparation methods: density gradient centrifugation and microfluidic sperm sorting using the Zymot Multi device. Participants will be assigned to one of the two methods while undergoing intrauterine insemination over a three-month treatment period. The study aims to evaluate the cumulative pregnancy outcomes of each method, with follow-up until 8-10 weeks of pregnancy to assess results. Standard treatment plans will be followed as designed by the participants' fertility physicians.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients undergoing intrauterine insemination
* Patient assigned female at birth with age \<41

Exclusion Criteria:

* Any significant disease or psychiatric disorder that would interfere with the consenting process
* Prior intrauterine insemination
* Use of frozen donor sperm
* Non-English speaker

Where it's running

• UCSF Center for Reproductive Health
  San Francisco, California, United States Recruiting

Study contacts

• Principal investigator: Mitchell Rosen, MD — University of California, San Francisco
• Study coordinator: Alisha T Tolani, MD
• Email: alisha.tolani@ucsf.edu
• Phone: 6282867307

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.