Comparing two methods of pain control after kidney surgery in cancer patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of two different techniques for administering quadratus lumborum plane blocks to manage postoperative pain in cancer patients undergoing open nephrectomy. The two methods being compared are the bilateral ultrasound-guided intramuscular quadratus lumborum plane block and the bilateral lateral quadratus lumborum plane block. By assessing pain relief and potential complications, the study aims to determine which technique provides better outcomes for patients. The research is conducted at the National Cancer Institute in Cairo, Egypt.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age from 18 to 65 years.
* Both sexes.
* American Society of Anesthesiology (ASA) physical status II-III.
* Body mass index (BMI): (20- 40) kg/m2.
* Type of surgery: midline incision for unilateral open nephrectomy.

Exclusion Criteria:

* Patient refusal.
* Age \<18 years or \>65 years
* BMI \<20 kg/m2 and \> 40 kg/m2
* Known sensitivity or contraindication to drugs used in the study
* Contraindication to regional anesthesia, e.g. local infection at the introduction site, pre-existing peripheral neuropathies and coagulopathy.
* Physical status ASA IV
* Patients on chronic analgesic therapy (daily morphine ≥30 mg or equivalent dose of other opioids or tramadol or any medication for neuropathic pain)
* Patients with a history of drug abuse
* Patients with neuropsychiatric diseases; patients with a history of chronic pain syndromes that may enhance sensitivity to pain, for example, fibromyalgia
* All patients who are going to have severe intra- or post-operative bleeding or will require postoperative mechanical ventilation are also excluded from the study.

Where it's running

• National Cancer Institute
  Cairo, Egypt Recruiting

Study contacts

• Study coordinator: Ahmed M Salama, Master
• Email: dr.Ahmed.ismail93@gmail.com
• Phone: 00201024275085

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.