Comparing two methods of deep brain stimulation for Parkinson's disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to compare the effectiveness and patient satisfaction of constant current versus constant voltage deep brain stimulation in patients with Parkinson's disease. It is a randomized, parallel controlled, multi-center trial involving approximately 180 participants who will be followed for up to 12 months after surgery. Participants will be assigned to either current mode or voltage mode of stimulation and will undergo comprehensive assessments at baseline and during follow-up. The study will evaluate programming burden, power consumption, and overall satisfaction from both physicians and patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with idiopathic Parkinson's disease
* Aged 18 to 75, no limited sex
* After bilateral STN-DBS, yet not powered on

Exclusion Criteria:

* Mental disorders or dementia
* Pregnant, lactating women or women who are unable to take effective measures to prevent pregnancy
* Serious health conditions, such as tumors, liver or kidney diseases, etc.
* Epilepsy or other seizure disorders
* Patients with severely deviated electrode placement
* Patients who were unable to voluntarily sign an informed consent form
* Patients who did not agree to cooperate with follow-up

Where it's running

• Xuanwu Hospital of Capital Medical University
  Beijing, China Recruiting

Study contacts

• Study coordinator: Shanshan Mei
• Email: sophy33@163.com
• Phone: +86 13426263236

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.