Comparing two methods for treating knee instability after ACL injuries

Evaluation of the Results of Two Different Methods in Management of Antero-lateral Instability of the Knee

NA · Sohag University · NCT06222814

This study is testing two different surgical methods to see which one helps people with knee instability after ACL surgery recover better and feel more stable.

Quick facts

PhaseNA
Study typeInterventional
Enrollment40 (estimated)
Ages18 Years to 45 Years
SexAll
SponsorSohag University (other)
Locations1 site (Sohag)
Trial IDNCT06222814 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the effectiveness of two surgical techniques for managing anterolateral instability of the knee following anterior cruciate ligament reconstruction (ACLR). Patients will be randomly assigned to receive either ACLR combined with anterolateral ligament reconstruction using a peroneus longus autograft or ACLR combined with extra-articular tenodesis (Modified Lemaire). The surgeries will be performed by the same surgical team using standardized techniques to ensure consistency in the results. The study will assess the outcomes of both methods to determine which provides better stability and recovery for patients.

Who should consider this trial

Good fit: Ideal candidates for this study are patients aged 18-45 with ACL deficiency and significant anterolateral instability confirmed by clinical examination and MRI.

Not a fit: Patients with multiple ligament injuries, significant articular cartilage defects, or those requiring revision surgeries may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved surgical techniques for knee instability, enhancing recovery and stability for patients with ACL injuries.

How similar studies have performed: While there have been studies on ACL reconstruction techniques, this specific comparison of anterolateral ligament reconstruction versus extra-articular tenodesis is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. The ACL deficient knee was clinically manifested by physical examination and confirmed by MRI.
2. Age 18-45 years, skeletally mature patient.
3. A positive pivot shift test of at least grade II is required (significant anterolateral instability).

Exclusion Criteria:

1. Multiple ligament injuries or a polytraumatized patient
2. Revision cases.
3. Generalized laxity.
4. Symptomatic articular cartilage defect requiring treatment; Outerbridge \> grade II.
5. More than three degrees of varus or valgus malalignment

Where this trial is running

Sohag

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Anterior Cruciate Ligament Injuries

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.