Comparing two methods for treating atrial fibrillation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized study compares pulsed field ablation and cryoballoon ablation in patients undergoing first-time atrial fibrillation catheter ablation. The focus is on assessing the quality of ablation lesions using late gadolinium enhancement cardiac magnetic resonance imaging three months post-ablation. Patients will be assigned in a 2:1 ratio to receive either pulsed field ablation or cryoballoon ablation for pulmonary vein isolation. The study aims to evaluate the efficacy and safety of these two ablation techniques.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients scheduled for first-time atrial fibrillation catheter ablation

Exclusion Criteria:

* age \<18 years
* long-standing persistent atrial fibrillation
* prior left atrial ablation
* pregnancy or lactation
* reduced left ventricular ejection fraction
* GFR \<30%
* BMI \>35%
* left atrial diameter \>55 mm
* cardiac implantable electronic device

Where it's running

• Hospital Clinic, University of Barcelona
  Barcelona, Catalonia, Spain Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.