Comparing two methods for removing kidney stones during ureteroscopy
Prospective, Randomized Study to Assess Patient Satisfaction and Stone Free Effect of High Powered Stone Dusting vs. Fragmentation and Basketing at Time of Ureteroscopy
NA · Northwestern University · NCT05006937
This study is testing two different ways to remove larger kidney stones during a procedure to see which method helps patients feel better and recover faster.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 168 (estimated) |
| Ages | 18 Years to 89 Years |
| Sex | All |
| Sponsor | Northwestern University (other) |
| Locations | 1 site (Chicago, Illinois) |
| Trial ID | NCT05006937 on ClinicalTrials.gov |
What this trial studies
This study aims to compare the effectiveness and patient satisfaction of two techniques for treating kidney stones 6 mm and larger during ureteroscopy: high-powered laser dusting and basket extraction. Participants will be randomly assigned to one of the two treatment groups, with the dusting method breaking stones into tiny fragments that can pass through urine, while the basket method involves physically removing stone fragments. After the procedure, patients will report their pain levels and daily activities through questionnaires until they recover. Follow-up assessments will include ultrasounds and standard imaging to check for any remaining stones.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 years old with kidney stones 6 mm or larger located in the mid ureter or higher.
Not a fit: Patients under 18, those with a solitary kidney, or individuals unable to provide informed consent may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment options for patients with larger kidney stones, enhancing recovery and satisfaction.
How similar studies have performed: Previous studies have shown promising results with similar laser dusting techniques, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * \>18 years of age * undergoing ureteroscopic stone extraction * Stone size 6mm stones or greater and the location to mid ureter or higher * Willing to sign informed consent form * Able to read, understand, and complete patient questionnaires, and pain questionnaires Exclusion Criteria: * \< 18 years of age * Inability to provide informed consent * Concomitant surgery (i.e. Percutaneous nephrolithotomy, Holmium laser enucleation of the prostate * Solitary kidney * Nephrocalcinosis * Members of vulnerable patient populations * Patients without access to a phone that can receive txt messages
Where this trial is running
Chicago, Illinois
- Northwestern Memorial Hospital — Chicago, Illinois, United States (RECRUITING)
Study contacts
- Principal investigator: Amy Krambeck, MD — Northwestern University
- Study coordinator: Matthew Lee, MD
- Email: matthew.lee@nm.org
- Phone: 3126958146
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Kidney Stone, Ureteral Stone