Clinical trial Recruiting at 1 site Interventional Ages 18 to 75

Comparing two methods for pain relief after minimally invasive heart surgery

Official title: Comparison of Ultrasound-Guided Serratus Combination Plane Blocks and Local Wound Infiltration for Postoperative Analgesia Management in Minimally Invasive Cardiac Surgery (MICS)

Run by İstanbul Yeni Yüzyıl Üniversitesi · NCT06968065 · Data updated 2026-11-12

This study is testing two different ways to relieve pain after minimally invasive heart surgery to see which one helps patients feel better and use fewer pain medications.

Quick facts

Study typeInterventional
Ages18 Years to 75 Years
SexAll
Enrollment60 (estimated)
Sponsorİstanbul Yeni Yüzyıl Üniversitesi
Academic / other
Locations1 site (Istanbul)
StatusRecruiting
StartedOctober 17, 2024
Main results expectedJune 2025
Study endsJune 2025
Registry record updatedMay 13, 2025
Trial IDNCT06968065 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18-75 undergoing minimally invasive cardiac surgery with specific incision criteria.

Probably not a fit

Patients with coagulopathy, allergies to local anesthetics or opioids, or those undergoing bilateral thoracic incisions may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of ultrasound-guided serratus anterior plane and serratus-intercostal interfascial plane blocks compared to local wound infiltration for managing postoperative pain in patients undergoing minimally invasive cardiac surgery. It is a randomized, prospective, single-blinded trial involving 60 patients, focusing on opioid consumption and pain scores post-surgery. The study aims to determine which method provides better analgesia and fewer complications during recovery.

Why it matters

Potential benefit: If successful, this approach could lead to improved pain management and reduced opioid use for patients after heart surgery.

How similar studies have gone: Previous studies have shown promising results with similar ultrasound-guided regional anesthesia techniques, suggesting potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 18-75 years
* Undergoing MICS with left-sided 4th-5th intercostal incision
* ASA I-III
* Informed consent provided

Exclusion Criteria:

* Coagulopathy or on anticoagulants

  * Allergy to local anesthetics or opioids
  * Local infection at block site
  * Pregnancy or lactation
  * Bilateral thoracic incisions
  * Refusal to participate

Where it's running

  • Kolan International Hospital
    Istanbul, Turkey (Türkiye)
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.