Comparing two methods for pain relief after minimally invasive heart surgery
Official title: Comparison of Ultrasound-Guided Serratus Combination Plane Blocks and Local Wound Infiltration for Postoperative Analgesia Management in Minimally Invasive Cardiac Surgery (MICS)
Run by İstanbul Yeni Yüzyıl Üniversitesi · NCT06968065 · Data updated 2026-11-12
This study is testing two different ways to relieve pain after minimally invasive heart surgery to see which one helps patients feel better and use fewer pain medications.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 75 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | İstanbul Yeni Yüzyıl Üniversitesi Academic / other |
| Locations | 1 site (Istanbul) |
| Status | Recruiting |
| Started | October 17, 2024 |
| Main results expected | June 2025 |
| Study ends | June 2025 |
| Registry record updated | May 13, 2025 |
| Trial ID | NCT06968065 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18-75 undergoing minimally invasive cardiac surgery with specific incision criteria.
✕Probably not a fit
Patients with coagulopathy, allergies to local anesthetics or opioids, or those undergoing bilateral thoracic incisions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of ultrasound-guided serratus anterior plane and serratus-intercostal interfascial plane blocks compared to local wound infiltration for managing postoperative pain in patients undergoing minimally invasive cardiac surgery. It is a randomized, prospective, single-blinded trial involving 60 patients, focusing on opioid consumption and pain scores post-surgery. The study aims to determine which method provides better analgesia and fewer complications during recovery.
Why it matters
Potential benefit: If successful, this approach could lead to improved pain management and reduced opioid use for patients after heart surgery.
How similar studies have gone: Previous studies have shown promising results with similar ultrasound-guided regional anesthesia techniques, suggesting potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18-75 years * Undergoing MICS with left-sided 4th-5th intercostal incision * ASA I-III * Informed consent provided Exclusion Criteria: * Coagulopathy or on anticoagulants * Allergy to local anesthetics or opioids * Local infection at block site * Pregnancy or lactation * Bilateral thoracic incisions * Refusal to participate
Where it's running
-
Kolan International Hospital
Istanbul, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Selcuk Alver, MD
- Email: alverselcuk@gmail.com
- Phone: +905435424234
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Using Exparel to control pain after MPFL reconstruction in kids
This study sees if adding Exparel to standard local anesthesia reduces post-op pain and opioid pill use in patients aged 13 and older having an isolated MPFL reconstruction.
-
Anterior Knee Nerves Block vs Femoral Nerve Block for Knee Arthroscopy
This trial tests whether an anterior nerves of the knee (ANK) block provides similar pain relief to a femoral nerve block after knee arthroscopy in adults, aiming to reduce quadriceps weakness.
-
Low-Volume PENG Block With Dexamethasone After Hip Replacement
This trial tests whether a smaller PENG block with dexamethasone provides similar pain relief but preserves quadriceps strength after hip replacement, compared with the standard-volume PENG block.
-
Esmolol vs Dexmedetomidine for opioid-sparing in laparoscopic gynecologic surgery
This study tests whether low-dose esmolol or dexmedetomidine, given during surgery, reduces opioid use and improves pain control after laparoscopic hysterectomy compared with placebo.
-
Analgesia after open inguinal hernia repair using intrathecal morphine or a transversalis fascia plane block
This trial tests whether intrathecal morphine or a ultrasound-guided transversalis fascia plane block can provide better pain relief after open inguinal hernia repair in adults.
-
Three nerve blocks for knee replacement: which one works best
This trial tests three different nerve blocks used during knee replacement to see which provides the best pain relief for patients after surgery.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.