Comparing two methods for pain relief after knee surgery
Genicular Nerve Block Versus Its Combination With Infiltration Between Popliteal Artery and Capsule of Posterior Knee for Enhanced Recovery After Total Knee Arthroplasty
This study tests whether a new way of managing pain after knee surgery, using a combination of two techniques, works better than just one method or standard pain relief for helping patients recover.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 63 (estimated) |
| Ages | 21 Years to 60 Years |
| Sex | All |
| Sponsor | Zagazig University Government |
| Locations | 1 site (Zagazig) |
| Trial ID | NCT05672784 on ClinicalTrials.gov |
What this trial studies
This study compares the effectiveness of a genicular nerve block (GNB) alone versus a combination of GNB and infiltration between the popliteal artery and the posterior capsule of the knee (IPACK) for managing postoperative pain in patients undergoing total knee replacement. The goal is to evaluate which method provides better pain control and enhances physical recovery following surgery. Participants will receive either GNB with standard analgesia, GNB with IPACK plus standard analgesia, or standard analgesia alone. The study aims to determine the optimal approach for improving postoperative outcomes.
Who should consider this trial
Good fit: Ideal candidates are adults aged 21 to 60 years undergoing elective total knee arthroplasty with a physical status of ASA I or II.
Not a fit: Patients with certain medical conditions such as peripheral vascular disease, heart issues, or those on specific medications may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management and faster recovery for patients after knee surgery.
How similar studies have performed: Other studies have shown promising results with similar nerve block techniques, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion criteria: * Adult patients aged between 21 to 60 years * undergoing primary unilateral elective total knee arthroplasty under spinal anesthesia * Having informed consents * patients with physical status ASA I \& II * both genders * body mass index less than 40 kg/m2. Exclusion criteria * patients with Peripheral vascular disease * patients with history of allergy to local anesthesia or opioid analgesia, * those on anti-platelet, anticoagulant or B blocker drugs * Patients with acute decompensated heart failure * Patients with hypertension * Patients with heart block * Patients with coronary disease * Patients with bronchial asthma * Patients with bleeding disorders * Patients with compromised renal or hepatic function * pregnant female.
Where this trial is running
Zagazig
- Heba M Fathi — Zagazig, Egypt (Recruiting)
Study contacts
- Study coordinator: Heba M Fathi, MD
- Email: heba_elgendi@yahoo.com
- Phone: 01000143938
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.