Comparing two methods for pain relief after knee surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study compares the effectiveness of a genicular nerve block (GNB) alone versus a combination of GNB and infiltration between the popliteal artery and the posterior capsule of the knee (IPACK) for managing postoperative pain in patients undergoing total knee replacement. The goal is to evaluate which method provides better pain control and enhances physical recovery following surgery. Participants will receive either GNB with standard analgesia, GNB with IPACK plus standard analgesia, or standard analgesia alone. The study aims to determine the optimal approach for improving postoperative outcomes.

Why it matters

Who can join: the full rules

Inclusion criteria:

* Adult patients aged between 21 to 60 years
* undergoing primary unilateral elective total knee arthroplasty under spinal anesthesia
* Having informed consents
* patients with physical status ASA I \& II
* both genders
* body mass index less than 40 kg/m2.

Exclusion criteria

* patients with Peripheral vascular disease
* patients with history of allergy to local anesthesia or opioid analgesia,
* those on anti-platelet, anticoagulant or B blocker drugs
* Patients with acute decompensated heart failure
* Patients with hypertension
* Patients with heart block
* Patients with coronary disease
* Patients with bronchial asthma
* Patients with bleeding disorders
* Patients with compromised renal or hepatic function
* pregnant female.

Where it's running

• Heba M Fathi
  Zagazig, Egypt Recruiting

Study contacts

• Study coordinator: Heba M Fathi, MD
• Email: heba_elgendi@yahoo.com
• Phone: 01000143938

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.