Comparing two methods for assessing lung function in children with respiratory distress
Official title: Comparison of Oxygenation Index and Oxygen Stretch Index With Mechanical Power, Driving Pressure, Transpulmonary Pressure, and Lung Ultrasound Scores in PARDS Patients
Run by Dr. Behcet Uz Children's Hospital · NCT06586411 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study is trying to see if a new way of measuring lung function can help doctors better understand and treat children with serious breathing problems.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 1 Month to 18 Years |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Dr. Behcet Uz Children's Hospital Academic / other |
| Locations | 7 sites (Aydın and 6 other locations) |
| Trial ID | NCT06586411 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are intubated pediatric patients diagnosed with pARDS.
✕Probably not a fit
Patients with perinatal lung disease, cardiac failure, or those whose respiratory mechanics cannot be measured will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to compare the Oxygenation Index (OI) and the Oxygen Stretch Index in pediatric patients diagnosed with Acute Respiratory Distress Syndrome (pARDS). It will evaluate various parameters such as transpulmonary pressure, mechanical power, and lung ultrasound scores to assess lung injury severity. The study seeks to determine if using driving pressure in the oxygenation index formula provides a better evaluation of pARDS compared to traditional methods. By analyzing these metrics, the study hopes to improve the understanding and management of respiratory failure in children.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic and treatment strategies for pediatric patients suffering from acute respiratory distress syndrome.
How similar studies have gone: Other studies have shown success in using similar approaches to assess lung injury in both adult and pediatric populations, indicating potential for this method.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * pARDS patient * Intubated patient Exclusion Criteria: * Perinatal lung disease * Cardiac failure and fluid overload * Patients whose respiratory mechanics cannot be measured * Age under 1 month or above 18 years old * ETT leakage \> 18%
Where it's running
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Aydin Obstetric and pediatrics Hospital
Aydın, Turkey Recruiting -
Erzurum Regional Research and Training Hospital
Erzurum, Turkey Recruiting -
Cam Sakura Research and Training Hospital
Istanbul, Turkey Recruiting -
Acibadem University, Acibadem Altunizade Hospital
Istanbul, Turkey Recruiting -
The Health Sciences University Izmir Behçet Uz Child Health and Diseases Research and Training Hospital
Izmir, Turkey Recruiting -
The Health Sciences University Izmir Behçet Uz Child Health and Diseases Research and Training Hospital
İzmir, Turkey Recruiting
Show 1 more location
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Istanbul Aydin University
Istanbul, Turkey Completed
Study contacts
- Study coordinator: Hasan Agin
- Email: Hasanagin@gmail.com
- Phone: +905362013162
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Optimizing lung pressure in children with respiratory distress using advanced imaging
This study is testing a new way to adjust breathing support in children with severe lung problems to see if it helps them breathe better than the usual methods.
-
Comparing closed-loop and conventional methods for ventilator synchronization in children
This study is testing a new way to help ventilators work better with children who need breathing support in the hospital to see if it helps them breathe more comfortably.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.