Comparing two laser ablation techniques for eye surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial is a prospective randomized contralateral double-masked study that aims to compare the visual outcomes of two different laser ablation techniques: wave-front optimized (WFO) and topography-guided (TG) during Photorefractive Keratectomy (PRK) or Laser-assisted in situ Keratomileusis (LASIK) surgery. Patients will be randomized to have one eye treated with WFO and the other with TG, allowing for a direct comparison of the effectiveness of these techniques. The study will involve a thorough preoperative evaluation and education, with a focus on optimizing visual outcomes and minimizing post-operative optical aberrations. The use of advanced technology, such as the VARIO Topolyzer, will help tailor the ablation pattern to individual patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Meet requirements for PRK or LASIK i.e., Stable \<= .5 D change MRSE)
* DOD beneficiaries age 21-50 years
* Local pts (w/i 60 mi) who will be in the area for at least 6 months post surgery
* Willing to complete all required follow-up visits

Exclusion Criteria:

* No meeting requirements for PRK or LASIK
* Desiring monovision treatment
* Anisometropia \>2D spherical equivalent
* Prior ocular surgeries / trauma / problem
* History of dry eyes
* Hyperopia
* Mixed astigmatism
* Inability to capture VARIO topolyzer scans
* Pregnant (or who plans to be within 6 months after surgery)
* Breastfeeding any time during the study
* History of herpetic disease

Where it's running

• Joint Warfighter Refractive Surgery Center at WHASC
  San Antonio, Texas, United States Recruiting

Study contacts

• Principal investigator: Charisma B Evangelista, Md — 59th Medical Wing
• Study coordinator: JOSE E CAPO-APONTE, OD, PhD
• Email: Jose.E.CapoAponte.ctr@health.mil
• Phone: 210-292-2554

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.