0.05 D precision refraction to improve SMILE and FS‑LASIK vision

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective study enrolls patients scheduled for SMILE or FS‑LASIK at the Affiliated Hospital of Nantong University and measures preoperative refraction with a binocular wavefront aberrometer at 0.05 D increments. The 0.05 D refraction values will be entered into the VisuMax Precision 4.0 system for SMILE or applied with the FS‑LASIK manufacturer nomogram to guide surgical input. Patients will be followed at 10 days, 1 month, 3 months, 6 months and 1 year to record uncorrected and best‑corrected visual acuity, spherical and cylindrical power, spherical equivalent, and higher‑order aberrations. Primary outcomes are postoperative UCVA and BCVA and the proportion of patients reaching specified UCVA thresholds, with secondary outcomes including residual refractive error and aberrations.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. The diopter is relatively stable (the diopter increases within -0.50D per year for 2 consecutive years);
2. Age: 18 to 40 years old;
3. Optimal preoperative corrected visual acuity \>= 4.8;
4. More than 2 weeks for soft contact lenses and more than 3 months for hard contact lenses before surgery
5. Patients who are willing to perform SMILE surgery

Exclusion Criteria:

1. Patients with history of eye surgery and trauma;
2. Patients with keratoconus tendency;
3. systemic connective tissue diseases and autoimmune diseases;
4. Patients with high blood pressure, diabetes and heart disease history;
5. Other eye disease history such as uveitis, scleritis and other eye inflammation patients;
6. Patients with scar constitution.

Where it's running

• Binocular Wavefront Optometry Machine
  Nantong, Jiangsu, China Recruiting

Study contacts

• Study coordinator: Ying Yu, MD
• Email: yuying.2009@163.com
• Phone: +86 159 9662 1616

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.