Comparing two imaging techniques for lung perfusion and ventilation
68Ga PET/CT Versus 99mTc SPECT/CT for Lung Perfusion and Ventilation Scintigraphy; a Technical and Practical Feasibility Study
NA · UMC Utrecht · NCT06246838
This study is testing a new type of lung imaging to see if it works better than the current method for adults who need to check for blood clots in their lungs.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | UMC Utrecht (other) |
| Locations | 1 site (Utrecht) |
| Trial ID | NCT06246838 on ClinicalTrials.gov |
What this trial studies
This study evaluates the feasibility of using 68Ga PET/CT imaging as an alternative to the traditional 99mTc SPECT/CT for lung perfusion and ventilation scintigraphy. It aims to address the limitations of the current SPECT/CT method, particularly for patients who cannot undergo conventional imaging due to various health concerns. Participants will be adults referred for a standard V/Q SPECT/CT due to suspected pulmonary embolism. The study will assess the practicality and effectiveness of the new imaging technique in detecting pulmonary embolisms.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who are referred for a conventional V/Q SPECT/CT due to known or suspected pulmonary embolism.
Not a fit: Patients who are pregnant will not benefit from this study due to exclusion criteria.
Why it matters
Potential benefit: If successful, this study could provide a more effective and safer imaging option for patients with suspected pulmonary embolism.
How similar studies have performed: International studies have shown promise in using 68Ga for imaging, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult ≥18 years and declared competent * Provided written informed consent * Referred to the Nuclear Medicine Department for a conventional V/Q-SPECT/CT * Indication for conventional V/Q-SPECT/CT includes known or suspected pulmonary embolism Exclusion Criteria: - Pregnancy
Where this trial is running
Utrecht
- UMC Utrecht — Utrecht, Netherlands (RECRUITING)
Study contacts
- Study coordinator: Arthur J.A.T. Braat, M.D. Ph.D.
- Email: a.j.a.t.braat@umcutrecht.nl
- Phone: +31887558855
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Pulmonary Embolism, Ventilation Perfusion Mismatch, Ga-68-MAA, Galligas, Tc-99m-MAA, Technegas, PET/CT, SPECT/CT