Comparing two doses of corticosteroids for frozen shoulder treatment

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the efficacy of two different doses of methylprednisolone (40 mg vs 80 mg) combined with hydrodilatation in treating adhesive capsulitis of the shoulder. The study will enroll 40 participants who will be randomly assigned to receive one of the two doses during an ultrasound-guided procedure. Pain reduction, shoulder mobility improvement, and side effects will be assessed through various questionnaires and measurements at baseline and four weeks post-treatment. The trial is designed as a double-blind study to ensure unbiased results.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* \>18 years of age
* Diagnostic of adhesive capsulitis of the shoulder

Exclusion Criteria:

* Injection received in the affected shoulder \< 3 months ago (any kind)
* History of previous surgery in the affected shoulder
* Glenohumeral osteoarthritis more than mild on the xray
* Pregnancy
* Blood thinner (other than Aspirin 80 mg) or bleeding disorder
* Active infection (requiring antibiotic)
* Allergy to steroid or lidocaine
* Cognitive impairment
* Active litigation
* Inflammatory connective tissue disorder

Where it's running

• Toronto Rehabilitation Institution
  Toronto, Ontario, Canada Recruiting

Study contacts

• Study coordinator: Nimish Mittal
• Email: nimish.mittal@uhn.ca
• Phone: 416-597-3422

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• TaVNS added to physiotherapy for adhesive capsulitis

  This study tests whether adding a tVNS treatment to standard physiotherapy helps adults with adhesive capsulitis reduce pain and improve shoulder function.

  Recruiting Liv Hospital Vadistanbul · Istanbul, Istanbul · NCT07711353

• Nexsphere-F arterial embolization for chronic frozen shoulder pain

  We will try a minimally invasive arterial embolization using Nexsphere-F to reduce pain in adults with frozen shoulder that hasn’t improved with usual care.

  Recruiting Chung-Ang University Hospital · Seoul · NCT07336849

• Hormone Replacement Therapy added to standard care for frozen shoulder in peri- or postmenopausal women

  This study tests whether adding hormone replacement therapy to standard treatment helps reduce pain and stiffness from frozen shoulder in peri- or postmenopausal women.

  Recruiting Phase 4 University of California, San Francisco · San Francisco, California · NCT07278323

• Evaluating non-invasive neurostimulation for frozen shoulder treatment

  This study is testing if a new non-invasive treatment using brain stimulation and tendon vibration can help people with frozen shoulder feel better compared to a placebo.

  Recruiting Université du Québec à Chicoutimi · Saguenay, Quebec · NCT06795932

• Evaluating robotic training for shoulder adhesive capsulitis

  This study is testing if robotic training can help adults with shoulder pain and movement issues recover better than regular rehab methods.

  Recruiting Mohammed V Souissi University · Rabat · NCT06766448

• High-intensity interval training for persistent inflammatory shoulder pain

  This study will try short sessions of high-intensity interval training (HIIT) in adults with long-term shoulder pain thought to be driven by low-grade inflammation to see if the exercise is acceptable and whether inflammation and pain-related measures change.

  Recruiting Universiteit Antwerpen · Wilrijk · NCT07275164

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.