Clinical trial Recruiting at 1 site Interventional Ages 18 to 25

Comparing three short running HIIT schedules for cardiometabolic health in young adults with obesity

Official title: Detraining Effect of Short-term HIIT on Cardiometabolic Risk in Young Adults With Obesity

Run by Syracuse University · NCT05838950 · Data updated 2026-11-12

This project will try three different short-term running HIIT schedules versus no training to see which best improves cardiometabolic markers in 18–25-year-olds with obesity.

More Obesity trials

Quick facts

Study typeInterventional
Ages18 Years to 25 Years
SexAll
Enrollment60 (estimated)
SponsorSyracuse University
Academic / other
Locations1 site (Syracuse, New York)
StatusRecruiting
StartedSeptember 29, 2023
Main results expectedAugust 23, 2025
Study endsDecember 10, 2025
Registry record updatedJuly 23, 2025
Trial IDNCT05838950 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are otherwise-healthy young adults aged 18–25 with BMI ≥ 30 kg/m2 who are not currently on weight-loss medications or enrolled in a weight-loss program and who can attend in-person sessions.

Probably not a fit

People with syndromic obesity, those taking medications or with medical conditions that affect carbohydrate or lipid metabolism, individuals with pacemakers, or pregnant persons are excluded and are unlikely to benefit from this protocol.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this randomized, four-arm trial participants are assigned to one of three running-based high-intensity interval training (HIIT) protocols or a no-exercise control and complete six supervised sessions over two weeks. The three HIIT arms differ by work-to-rest timing (short, medium, and longer sprint intervals) while intensity is set near 90% of fastest baseline performance and heart rate is recorded during sessions. Primary cardiometabolic outcomes include blood lipids, fasting glucose, blood pressure, insulin sensitivity indicators, and pulse wave velocity measured at baseline, immediately after the intervention, and again two weeks later to capture detraining effects. All training and testing are conducted in-person at Syracuse University and measurements are timed to avoid acute effects of the final session.

Why it matters

Potential benefit: If successful, the results could identify which brief HIIT format most effectively improves blood lipids, blood pressure, and glucose control in obese young adults and help tailor exercise prescriptions.

How similar studies have gone: Previous research shows HIIT can improve cardiometabolic markers in overweight adults, but direct comparisons of multiple very-short HIIT formats and short-term detraining responses are limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Young adults with obesity (Age 18 to 25 years old, BMI ≥ 30 kg/m2).

Exclusion Criteria:

* Syndromic obesity; 1) Any clinical symptoms including cognitive delay, 2) abnormalities in body structure(s), 3) organ-specific abnormalities (kidney, liver failure, excessive eating, and/or other signs of hypothalamic dysfunction such as fatigue, weakness and/or lack of interest in activities.
* Taking weight loss medication(s)
* Currently enrolled (or within previous 6 months) in a weight loss program;
* An underlying disease/medications (steroids, second generation psychotropic agents, hormonal contraception, statins, antihypertensive and antidiabetic medications) that could influence carbohydrate or lipid metabolism.
* Presence of cardiac pacemaker.
* Current or anticipated participation in another research that would interfere with any of the outcomes.
* Current or anticipated pregnancy.

Where it's running

  • Women's Building
    Syracuse, New York, United States
    Recruiting

Study contacts

  • Principal investigator: Joon Young Kim, Ph.D — Syracuse University, Departments of Exercise Science
  • Study coordinator: Myong Won Seo, Ph.D
  • Email: mseo04@syr.edu
  • Phone: 3154012723

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.