Comparing the health of babies born from IVF and IVM at age five
Long-term Developmental and Behavioral Outcomes of Children Born From CAPA-IVM Versus Conventional IVF at 5-year-old
This study looks at how babies born from two different fertility treatments, IVF and IVM, are doing at age five to see if there are any differences in their growth and development.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 231 (estimated) |
| Ages | 5 Years to 5 Years |
| Sex | All |
| Sponsor | Mỹ Đức Hospital Academic / other |
| Locations | 1 site (Ho Chi Minh City, Tan Binh) |
| Trial ID | NCT06369415 on ClinicalTrials.gov |
What this trial studies
This observational study follows up on children born from In-vitro Maturation (IVM) and conventional In-vitro Fertilization (IVF) to assess their developmental outcomes at five years of age. The study aims to determine if there are any significant differences in physical, mental, and motor development between the two groups using standardized assessment tools like the Ages & Stages Questionnaires (ASQ-3) and Strength and Difficulties Questionnaires (SDQ). Previous studies indicated no significant differences at earlier ages, and this research seeks to provide further evidence regarding the long-term safety and developmental impact of IVM in women with high antral follicle counts.
Who should consider this trial
Good fit: Ideal candidates for this study are children born from IVM or IVF who participated in previous follow-up studies.
Not a fit: Patients who may not benefit from this study include those whose babies died before 60 months.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the long-term safety and developmental outcomes of children born from IVM compared to conventional IVF.
How similar studies have performed: Other studies have shown no significant differences in early developmental outcomes between IVM and IVF, suggesting a potential for similar findings in this longer follow-up.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All babies born following the In-vitro Maturation and In-vitro fertilization from our FM study (NCT03405701) participated in our previous follow-up study (NCT04296357) * Parents agree to participate in the study. Exclusion Criteria: * Babies died under or at 60 months
Where this trial is running
Ho Chi Minh City, Tan Binh
- Mỹ Đức Hospital — Ho Chi Minh City, Tan Binh, Vietnam (Recruiting)
Study contacts
- Principal investigator: Lan N Vuong, MD, PhD — Mỹ Đức Hospital
- Study coordinator: Nghia A Nguyen, MD, PhD
- Email: nghianguyen@ump.edu.vn
- Phone: +84903199796
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.