Comparing the effects of two medications for endometriosis
Far Eastern Memorial Hospital
This study is testing which medication, dienogest or danazol, works better for women over 20 with endometriosis to help relieve their symptoms.
Quick facts
| Phase | Phase 3 |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | 20 Years and up |
| Sex | Female |
| Sponsor | Far Eastern Memorial Hospital Academic / other |
| Locations | 1 site (Banqiao, New Taipei) |
| Trial ID | NCT05697471 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the efficacy of two treatments, dienogest and danazol, for women suffering from endometriosis-related conditions such as adenomyosis. Women over 20 years old with diagnosed endometriosis will be randomly assigned to receive either dienogest or danazol. The study will assess symptom severity and perform examinations at baseline, 4 weeks, and 16 weeks after treatment to determine which medication is more effective.
Who should consider this trial
Good fit: Ideal candidates are women over 20 years old diagnosed with endometriosis or related conditions.
Not a fit: Patients with a history of breast cancer or other cancers, or those with vascular obstruction, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide clearer guidance on the most effective medication for treating endometriosis, improving patient outcomes.
How similar studies have performed: While there have been studies on the individual effects of dienogest and danazol, this direct comparison in a randomized setting is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * \> 20 years old * Have an endometriosis-related condition (including adenomyosis, adenomyoma, ovarian endometrioma, or pelvic endometriosis). Exclusion Criteria: * Minors. * Have a history of breast cancer or other cancers. * Patients with vascular obstruction such as stroke.
Where this trial is running
Banqiao, New Taipei
- Department of Obstetrics and Gynecology, Far Eastern Memorial Hospital — Banqiao, New Taipei, Taiwan (Recruiting)
Study contacts
- Study coordinator: Sheng-Mou Hsiao, MD
- Email: smhsiao2@gmail.com
- Phone: +886289667000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.