Comparing the effects of different anesthesia types on pupil response after surgery
Infrared Pupillometry - Effects of Different Types of General Anesthesia on Postoperative Pupillary Reactivity
This study is testing whether different types of anesthesia affect how well your pupils respond after ENT surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 108 (estimated) |
| Ages | 18 Years to 99 Years |
| Sex | All |
| Sponsor | Medical University of Vienna Academic / other |
| Locations | 1 site (Vienna, State of Vienna) |
| Trial ID | NCT04307238 on ClinicalTrials.gov |
What this trial studies
This study aims to compare the effects of volatile and intravenous anesthetics on pupillary function in patients undergoing elective Ear, Nose and Throat (ENT) surgery. It employs a monocentric, prospective, double-blinded randomized design, where participants will be assigned to receive either intravenous or inhalative anesthesia. Postoperative pupillary reactivity will be monitored using a portable infrared pupillometer to assess changes in pupillary light reflex. The findings may provide insights into postoperative vigilance and readiness for discharge.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 99 years undergoing elective ENT surgery under general anesthesia with an ASA classification of I-II.
Not a fit: Patients with a history of mental illness, neurological diseases, or those taking certain medications may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved assessments of postoperative recovery and readiness for discharge, potentially reducing complications and readmission rates.
How similar studies have performed: While the specific approach of using pupillometry for this purpose may be novel, similar studies have explored the effects of anesthesia on postoperative recovery with varying degrees of success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged ≥ 18 and ≤99 years * ASA I-II * Patients undergoing elective ENT surgery under general anesthesia Exclusion Criteria: * Patients aged \< 18 and \>99 years * consumption of antidepressants, tranquilizer, psychotropic medications * history of mental illness, neurosurgery, neurological or psychiatric disease * ophthalmologic disease * preexisting cognitive impairment * Patients with drug dependence, alcoholism * the patients' inability to follow procedures * implanted electronic medical devices
Where this trial is running
Vienna, State of Vienna
- Medical University Vienna — Vienna, State of Vienna, Austria (Recruiting)
Study contacts
- Study coordinator: Marita Windpassinger, MD
- Email: marita.windpassinger@meduniwien.ac.at
- Phone: +43 1 40400 41020
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.