Comparing the effects of different anesthesia types on pupil response after surgery
Official title: Infrared Pupillometry - Effects of Different Types of General Anesthesia on Postoperative Pupillary Reactivity
Run by Medical University of Vienna · NCT04307238 · Data updated 2026-11-12
This study is testing whether different types of anesthesia affect how well your pupils respond after ENT surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 99 Years |
| Sex | All |
| Enrollment | 108 (estimated) |
| Sponsor | Medical University of Vienna Academic / other |
| Locations | 1 site (Vienna, State of Vienna) |
| Status | Recruiting |
| Started | March 9, 2020 |
| Main results expected | March 10, 2026 |
| Study ends | March 10, 2026 |
| Registry record updated | July 4, 2025 |
| Trial ID | NCT04307238 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 to 99 years undergoing elective ENT surgery under general anesthesia with an ASA classification of I-II.
✕Probably not a fit
Patients with a history of mental illness, neurological diseases, or those taking certain medications may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to compare the effects of volatile and intravenous anesthetics on pupillary function in patients undergoing elective Ear, Nose and Throat (ENT) surgery. It employs a monocentric, prospective, double-blinded randomized design, where participants will be assigned to receive either intravenous or inhalative anesthesia. Postoperative pupillary reactivity will be monitored using a portable infrared pupillometer to assess changes in pupillary light reflex. The findings may provide insights into postoperative vigilance and readiness for discharge.
Why it matters
Potential benefit: If successful, this study could lead to improved assessments of postoperative recovery and readiness for discharge, potentially reducing complications and readmission rates.
How similar studies have gone: While the specific approach of using pupillometry for this purpose may be novel, similar studies have explored the effects of anesthesia on postoperative recovery with varying degrees of success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged ≥ 18 and ≤99 years * ASA I-II * Patients undergoing elective ENT surgery under general anesthesia Exclusion Criteria: * Patients aged \< 18 and \>99 years * consumption of antidepressants, tranquilizer, psychotropic medications * history of mental illness, neurosurgery, neurological or psychiatric disease * ophthalmologic disease * preexisting cognitive impairment * Patients with drug dependence, alcoholism * the patients' inability to follow procedures * implanted electronic medical devices
Where it's running
-
Medical University Vienna
Vienna, State of Vienna, Austria Recruiting
Study contacts
- Study coordinator: Marita Windpassinger, MD
- Email: marita.windpassinger@meduniwien.ac.at
- Phone: +43 1 40400 41020
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.