Comparing the Biograph Vision 600 and the Biograph Vision.X PET/CT scanners
Official title: Intra-individual Comparison of PET Scans on the Biograph Vision 600 With the New Biograph Vision.X PET/CT
Run by University Hospital, Geneva · NCT07006155 · Data updated 2026-11-12
This will test whether the Biograph Vision.X PET/CT scanner provides clearer images and better diagnostic results than the Biograph Vision 600 for adults with cancer or Alzheimer's disease.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 85 Years |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | University Hospital, Geneva Academic / other |
| Locations | 1 site (Geneva) |
| Status | Recruiting |
| Started | May 1, 2025 |
| Main results expected | May 30, 2026 |
| Study ends | May 30, 2026 |
| Registry record updated | June 5, 2025 |
| Trial ID | NCT07006155 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18 to 85 with cancer or Alzheimer disease who can provide written informed consent and lie still for a PET/CT exam are ideal candidates.
✕Probably not a fit
Pregnant people and anyone unable to lie still for the duration of the PET/CT scan are excluded and unlikely to receive benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This project collects clinical PET/CT images acquired on two Siemens Biograph systems to compare image quality and diagnostic performance. Adults referred for PET/CT because of cancer or suspected/known Alzheimer disease will be enrolled if they can give consent and lie still for the scan. Images from the Vision 600 and the newer Vision.X system will be reviewed and compared by readers using standardized image-quality and diagnostic criteria. The work is performed at the University Hospitals of Geneva and focuses on initial clinical experience with the Vision.X hardware.
Why it matters
Potential benefit: If successful, the Vision.X could produce clearer images that help clinicians detect disease more accurately and plan treatment better.
How similar studies have gone: Prior comparisons of newer versus older PET/CT hardware have generally shown improved image quality and diagnostic accuracy, though specific data directly comparing Vision.X to Vision 600 are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Written Inform Consent to participating. * 18 to 85 years of age * Willing and able to comply with the requirements of the study, as judged by the investigator Exclusion Criteria: * Women in pregnancy * Patients unable to lie still for the duration of the examination
Where it's running
-
Hopitaux Universitaires de Genève
Geneva, Switzerland Recruiting
Study contacts
- Study coordinator: Pr Valentina Garibotto Head of the Division of nuclear medicine and molecular imaging, MD
- Email: valentina.garibotto@hug.ch
- Phone: +41223727252
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.