Comparing the Biograph Vision 600 and the Biograph Vision.X PET/CT scanners

Intra-individual Comparison of PET Scans on the Biograph Vision 600 With the New Biograph Vision.X PET/CT

NA · University Hospital, Geneva · NCT07006155

This will test whether the Biograph Vision.X PET/CT scanner provides clearer images and better diagnostic results than the Biograph Vision 600 for adults with cancer or Alzheimer's disease.

Quick facts

PhaseNA
Study typeInterventional
Enrollment40 (estimated)
Ages18 Years to 85 Years
SexAll
SponsorUniversity Hospital, Geneva (other)
Locations1 site (Geneva)
Trial IDNCT07006155 on ClinicalTrials.gov

What this trial studies

This project collects clinical PET/CT images acquired on two Siemens Biograph systems to compare image quality and diagnostic performance. Adults referred for PET/CT because of cancer or suspected/known Alzheimer disease will be enrolled if they can give consent and lie still for the scan. Images from the Vision 600 and the newer Vision.X system will be reviewed and compared by readers using standardized image-quality and diagnostic criteria. The work is performed at the University Hospitals of Geneva and focuses on initial clinical experience with the Vision.X hardware.

Who should consider this trial

Good fit: Adults aged 18 to 85 with cancer or Alzheimer disease who can provide written informed consent and lie still for a PET/CT exam are ideal candidates.

Not a fit: Pregnant people and anyone unable to lie still for the duration of the PET/CT scan are excluded and unlikely to receive benefit from participation.

Why it matters

Potential benefit: If successful, the Vision.X could produce clearer images that help clinicians detect disease more accurately and plan treatment better.

How similar studies have performed: Prior comparisons of newer versus older PET/CT hardware have generally shown improved image quality and diagnostic accuracy, though specific data directly comparing Vision.X to Vision 600 are limited.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Written Inform Consent to participating.
* 18 to 85 years of age
* Willing and able to comply with the requirements of the study, as judged by the investigator

Exclusion Criteria:

* Women in pregnancy
* Patients unable to lie still for the duration of the examination

Where this trial is running

Geneva

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Cancer, Alzheimer Disease, PET/CT, Vision, image quality, diagnostic performance

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.