Comparing success of pulpotomy in molars with and without apical periodontitis using AI
Success Rate of Full Pulpotomy in Mature Permanent Molars with Irreversible Pulpitis with Apical Periodontitis Detected Using Artificial Intelligence and Those Without Apical Periodontitis: a Randomized Controlled Trial
This study is testing if a dental procedure called pulpotomy works better in molars with or without a specific infection, using AI to help identify the infection.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 58 (estimated) |
| Ages | 20 Years to 45 Years |
| Sex | All |
| Sponsor | Misr International University Academic / other |
| Locations | 1 site (Cairo, Obour) |
| Trial ID | NCT06767371 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the success rates of full pulpotomy in mature permanent molars diagnosed with irreversible pulpitis, comparing cases with apical periodontitis detected by AI to those without. Patients will be divided into two groups based on the presence or absence of apical periodontitis, and the accuracy of AI technology in identifying this condition from radiographs will be assessed against clinical observations. The study seeks to provide insights into the predictability of pulpotomy as a treatment option for these conditions.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 20 to 45 with mature permanent molars diagnosed with irreversible pulpitis, either with or without apical periodontitis.
Not a fit: Patients with non-vital teeth, immature roots, or those with initial and mild pulpitis may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a less invasive treatment option for patients with irreversible pulpitis, potentially reducing the need for root canal treatments.
How similar studies have performed: Other studies have shown promising results for similar approaches in vital pulp therapy, indicating potential for success in this novel application.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Presence of vital mature permanent molars diagnosed as severe irreversible pulpitis with apical periodontitis diagnosed clinically and radiographically and cases diagnosed as moderate irreversible pulpitis without apical periodontitis diagnosed clinically and radiographically per Wolter's classification. * Participants of both genders falling within the age range of 20 to 45 years. * Confirmation of vital bleeding pulp tissue in all canals following complete pulpotomy. Exclusion Criteria: * Non-vital tooth * Moderate pulpitis with apical periodontitis * Teeth with Immature roots * Uncontrolled pulpal bleeding persisting beyond 10 minutes post-application of sodium hypochlorite as a hemostatic agent. * Insufficient bleeding post-pulp exposure, indicative of pulp degeneration. * Cases categorized as initial and mild pulpitis per Wolter's classification.
Where this trial is running
Cairo, Obour
- Misr International University — Cairo, Obour, Egypt (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.