Comparing standard and intensive rehabilitation and nutrition for ICU patients
Standard vs Intensive Rehabilitation and Nutrition Regimen for Inpatients at the Intensive Care Unit
This study is testing whether a more intense rehabilitation and nutrition plan can help older ICU patients recover better and faster than the standard approach.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital Ostrava Academic / other |
| Locations | 1 site (Ostrava, Czech Republic) |
| Trial ID | NCT05209763 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the effectiveness of standard versus intensive rehabilitation and nutrition regimens for patients admitted to the Intensive Care Unit (ICU) due to acute internal illnesses. It focuses on maintaining physical fitness and self-sufficiency in older patients who often experience muscle mass loss and deterioration in overall fitness during hospitalization. By implementing targeted physiotherapy and nutrition strategies, the study seeks to determine which approach leads to better outcomes, including reduced length of hospital stay and improved functional ability. The study will involve patients who are expected to stay in the ICU for at least five days and can provide informed consent.
Who should consider this trial
Good fit: Ideal candidates include older patients admitted to the ICU for acute internal illnesses who can participate in rehabilitation and nutrition interventions.
Not a fit: Patients with terminal diseases, severe chronic conditions affecting digestion, or those who are fully immobile may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved rehabilitation protocols that enhance recovery and quality of life for ICU patients.
How similar studies have performed: Previous studies on intensive rehabilitation have shown mixed results, indicating that while early rehabilitation may influence muscle mass, its impact on critical endpoints remains inconclusive.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * male and female * patient admitted to the Intensive Care Unit of the Department of Internal Medicine and Cardiology, University Hospital Ostrava, for an acute illness of an internal nature; patients admitted to another department of the hospital whose transfer to the above-mentioned ICU (intensive care unit) was carried out within 24 hours of the start of hospitalization may also be included * assumption of a minimum length of hospital stay of 5 days * ability to give informed consent * the patient has both lower limbs * the patient can receive fluids and liquid food orally Exclusion Criteria: * patient admitted from another health care facility where he/she has been admitted for more than 48 hours * terminal stage of disease (tumor or non-tumor) * patient with neuromuscular disease (polymyositis, etc.) * severe chronic disease associated with severe maldigestion (e.g., patient on parenteral home nutrition) * patient is fully immobile for a long time
Where this trial is running
Ostrava, Czech Republic
- University Hospital Ostrava — Ostrava, Czech Republic, Czechia (Recruiting)
Study contacts
- Study coordinator: Zdenek Lys, M.D.
- Email: zdenek.lys@fno.cz
- Phone: 1420736541342
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.