Comparing sphenopalatine block and BOTOX for chronic migraine relief

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial evaluates the effectiveness and safety of two treatments for chronic migraine: sphenopalatine ganglion block (SPGB) and intramuscular BOTOX injections. Chronic migraine is characterized by headaches occurring 15 or more days per month, with specific criteria for migraine episodes. The study aims to determine which treatment provides better relief for patients suffering from this debilitating condition. Participants will be monitored for their response to each intervention over a defined period.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 and 65 years.
* Both sexes.
* Chronic migraine. Chronic migraine, defined as headaches on ≥15 days per month for ≥3 months, of which ≥8 days meet criteria for migraine without aura or respond to migraine-specific treatment according to International Classification of Headache Disorders-3 Beta.

Exclusion Criteria:

* Patients with medication over use headache.
* Bleeding disorders.
* Abnormal neurological examination.
* History of allergy to local anesthetics or BOTOX.

Where it's running

• Cairo University
  Cairo, Egypt Recruiting

Study contacts

• Study coordinator: Mohamed E Abdel Fattah, MD
• Email: mohamed-elsaid@cu.edu.eg
• Phone: 00201284475792

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.