Comparing SPECT-CT and MRI for diagnosing foot and ankle osteoarthritis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the diagnostic performance of SPECT-CT and MRI in patients with symptomatic osteoarthritis of the ankle, hindfoot, and midfoot. It involves a prospective cohort design where patients aged 18 and older, referred to the Martini Hospital Groningen, will undergo both imaging techniques as part of their standard workup. The study will assess parameters such as sensitivity, specificity, and predictive values to determine which imaging modality provides better diagnostic accuracy. The findings could help standardize diagnostic protocols for osteoarthritis in these areas.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Suspected symptomatic ankle, hind- or midfoot OA
* Informed consent
* Age ≥ 18 years
* Average NRS ≥4 over the past week.

Exclusion Criteria:

* Contraindication for surgery
* Contraindication for SPECT-CT or MRI
* Contraindication for intra-articular injections
* Isolated forefoot pathology
* Fracture, ligamentous or tendon injury of the ankle, hind- and/or midfoot trauma within one year before presentation
* History of neurological disease
* History of foot and/or ankle surgery (affected side)
* Inability to read and understand the written information

Where it's running

• Martini Hospital
  Groningen, Netherlands Recruiting

Study contacts

• Principal investigator: Tom van Raaij, MD/PhD — Martini Ziekenhuis
• Study coordinator: Arthur van Hasselt, MD
• Email: a.vanHasselt@mzh.nl
• Phone: 0031646345384

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.