Comparing smoking cessation methods for lung cancer screening patients
Official title: Providing Tobacco Treatment to Patients Undergoing Lung Cancer Screening at MedStar Health: A Randomized Trial (Tobacco Education and Lung Health Study)
Run by Georgetown University · NCT06290869 · Data updated 2026-11-12
This study tests two different ways to help people quit smoking who are getting screened for lung cancer to see which method works better.
Quick facts
| Phase | Phase 3 |
|---|---|
| Study type | Interventional |
| Ages | 50 Years to 80 Years |
| Sex | All |
| Enrollment | 1188 (estimated) |
| Sponsor | Georgetown University Academic / other |
| Locations | 1 site (Washington D.C., District of Columbia) |
| Status | Recruiting |
| Started | February 22, 2024 |
| Main results expected | December 1, 2027 |
| Study ends | March 1, 2028 |
| Registry record updated | February 17, 2026 |
| Trial ID | NCT06290869 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are English-speaking individuals aged 50-80 who are eligible for lung cancer screening and currently smoke cigarettes.
✕Probably not a fit
Patients with a prior lung cancer diagnosis, hearing or cognitive impairments, or those whose household members are already enrolled in the study may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to evaluate the effectiveness of two smoking cessation interventions among individuals undergoing lung cancer screening. It focuses on improving treatment delivery to underserved populations and assesses both self-reported and bioverified abstinence from cigarettes at three and six months. The study also includes an economic analysis to evaluate the costs of the interventions from a health system perspective. By integrating cessation treatment with lung cancer screening, the study seeks to enhance patient outcomes and reduce lung cancer deaths.
Why it matters
Potential benefit: If successful, this study could significantly improve smoking cessation rates among high-risk individuals, leading to better lung health and reduced lung cancer mortality.
How similar studies have gone: Other studies have shown success in integrating smoking cessation interventions with lung cancer screening, making this approach both relevant and promising.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * eligible for a screening or diagnostic scan, * USPSTF eligibility criteria (50-80 years old and \>20-pack years); * currently smoking cigarettes (\>1 in the past 30 days); * English speaking; * able to provide meaningful consent. Exclusion Criteria: * prior lung cancer, * hearing impairment, * cognitive impairment, * household member already enrolled.
Where it's running
-
Georgetown University Medical Center
Washington D.C., District of Columbia, United States Recruiting
Study contacts
- Study coordinator: Kathryn L Taylor, PhD
- Email: taylorkl@georgetown.edu
- Phone: 2022159402
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Quitting Matters: a smoking quit program for people living with HIV
This 6-month program will test whether a tailored smartphone app plus nicotine patches and gum helps people living with HIV quit smoking better than a standard quit app.
-
Smoky Futures: Danish Adolescent Nicotine Use over Time
This observational cohort follows Danish youths ages 15–25 to see how cigarette, e-cigarette, and other nicotine use begin, change, and affect health and education over several years.
-
Nicotine Orodispersible Tablet to Relieve Cravings in Smokers
A nicotine mint orodispersible tablet is tested vs placebo to see if it quickly eases the urge to smoke in adult cigarette smokers.
-
Optimizing when weekly chatbot reminders go out to people using a chatbot for quitting smoking
This study tests whether sending weekly reminders at different times helps people stay engaged with a chatbot smoking-cessation service.
-
NMDA and Sigma-1 combination therapy for smoking cessation with AXS-05
This phase 3 trial tests whether AXS-05 can help adults quit smoking better than placebo or bupropion.
-
AI-assisted interactive case-based training to improve smoking cessation counseling by medical interns
This study tests whether AI-powered interactive case-based training helps medical interns provide better smoking cessation counseling.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.