Comparing smoking cessation methods for lung cancer screening patients

Providing Tobacco Treatment to Patients Undergoing Lung Cancer Screening at MedStar Health: A Randomized Trial (Tobacco Education and Lung Health Study)

PHASE3 · Georgetown University · NCT06290869

This study tests two different ways to help people quit smoking who are getting screened for lung cancer to see which method works better.

Quick facts

PhasePHASE3
Study typeInterventional
Enrollment1188 (estimated)
Ages50 Years to 80 Years
SexAll
SponsorGeorgetown University (other)
Locations1 site (Washington D.C., District of Columbia)
Trial IDNCT06290869 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the effectiveness of two smoking cessation interventions among individuals undergoing lung cancer screening. It focuses on improving treatment delivery to underserved populations and assesses both self-reported and bioverified abstinence from cigarettes at three and six months. The study also includes an economic analysis to evaluate the costs of the interventions from a health system perspective. By integrating cessation treatment with lung cancer screening, the study seeks to enhance patient outcomes and reduce lung cancer deaths.

Who should consider this trial

Good fit: Ideal candidates for this study are English-speaking individuals aged 50-80 who are eligible for lung cancer screening and currently smoke cigarettes.

Not a fit: Patients with a prior lung cancer diagnosis, hearing or cognitive impairments, or those whose household members are already enrolled in the study may not benefit.

Why it matters

Potential benefit: If successful, this study could significantly improve smoking cessation rates among high-risk individuals, leading to better lung health and reduced lung cancer mortality.

How similar studies have performed: Other studies have shown success in integrating smoking cessation interventions with lung cancer screening, making this approach both relevant and promising.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* eligible for a screening or diagnostic scan,
* USPSTF eligibility criteria (50-80 years old and \>20-pack years);
* currently smoking cigarettes (\>1 in the past 30 days);
* English speaking;
* able to provide meaningful consent.

Exclusion Criteria:

* prior lung cancer,
* hearing impairment,
* cognitive impairment,
* household member already enrolled.

Where this trial is running

Washington D.C., District of Columbia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Smoking Cessation, high risk for lung cancer

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.