Comparing saline irrigation and povidone-iodine for preventing infections in emergency surgeries

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the effectiveness of high-volume saline irrigation versus povidone-iodine solution in preventing superficial surgical site infections (SSIs) in patients undergoing emergency laparotomies. Participants will be randomly assigned to receive either saline irrigation or conventional closure without irrigation before their incisions are closed. The study will measure the incidence of SSIs and the length of hospital stays following the interventions. By comparing these two methods, the trial seeks to identify the more effective approach for reducing infection rates in surgical settings.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* • Patients undergoing emergency laparotomy under the care of surgical-6 unit of Dr. Ruth K. M. Pfau Civil Hospital Karachi

  * The age of patients should be between 18-60 years old.

Exclusion Criteria:

* Diabetic patients
* Immune-suppressed patients
* Patients taking steroids
* Patients undergoing chemo-radiotherapy.
* Pregnant females
* Previous abdominal surgery within the last 30 days.
* Presence of concurrent abdominal wall infections.
* Trauma Laparotomies
* Large Bowel perforations

Where it's running

• Dr. Ruth K. M. Pfau Civil Hospital Karachi
  Karachi, Sindh, Pakistan Recruiting

Study contacts

• Principal investigator: Omer Bin Khalid, Assist Prof. — Dr. Ruth F. M. Pfau Civil Hospital Karachi
• Study coordinator: Omer Bin Khalid, Assist Prof.
• Email: dromerkhalid@gmail.com
• Phone: +92 321 2040064

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.