Comparing robotic and laparoscopic surgery for left-sided colon cancer
Functional Recovery and Oncologic Efficacy of Robotic Versus Laparoscopy NOSE for Patients With Stage I III Left Sided Colon Cancer: A Randomized Controlled Trial
NA · National Taiwan University Hospital · NCT05970133
This study is testing if robotic surgery can help people with left-sided colon cancer recover better and have fewer complications compared to traditional laparoscopic surgery.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 300 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | National Taiwan University Hospital (other) |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Taipei) |
| Trial ID | NCT05970133 on ClinicalTrials.gov |
What this trial studies
This project aims to provide level 1 evidence comparing robotic surgery to laparoscopic natural orifice specimen extraction (NOSE) for patients with stage I-III left-sided colorectal cancer. The study hypothesizes that robotic surgery, with its enhanced maneuverability, may offer better outcomes than traditional laparoscopic methods. The focus is on reducing postoperative complications associated with specimen retrieval through conventional incisions. The trial will involve patients undergoing elective surgery for curative resection of specified left-sided colon cancers.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 with stage I-III left-sided colon cancers requiring elective surgery.
Not a fit: Patients with cancers located in the cecal, ascending, or middle transverse colon, as well as those requiring emergency or palliative surgery, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical outcomes and reduced postoperative complications for patients with left-sided colorectal cancer.
How similar studies have performed: Previous studies have shown promising results for laparoscopic NOSE procedures, indicating potential for success with robotic approaches as well.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Primary colon cancers located at the left sided colonic anatomic location, including distal transverse colon, colonic splenic flexure, descending colon, sigm oid descending colonic junction, sigmoid colon and upper rectum that required the mobilization of colonic splenic flexure to facilitate a curative resection and trans anal specimen extraction ; 2. TNM Stage I III adenocarcinomas; 3. Curative and elective surgery; 4. American Society of Anesthesiology (ASA) class I to III patients; 5. Age \>18 years. Exclusion Criteria: 1. Cecal, ascending, the proximal and middle transverse colon cancers; and the middle or lower rectal cancers; 2. Emergency or palliative surgery; 3. Evidence of disseminated disease or adjacent organ invasion; 4. Primary tumor mass \>8 cm in diameter; 5. Morbidly obese patients, that is, body mass index (BMI) ≥40 kg/m 2 ; 6. Previous major surgery of upper abdomen or pelvis
Where this trial is running
Taipei
- National Taiwan University Hospital — Taipei, Taiwan (RECRUITING)
Study contacts
- Study coordinator: Jin-Tung LIANG, MD
- Email: jintung@ntu.edu.tw
- Phone: 886-9-72651432
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Colorectal Cancer, Colorectal cancer, Natural orifice specimen extraction, Laparoscopic surgery, Robotic surgery