Comparing rivaroxaban and enoxaparin for preventing blood clots in obese patients undergoing weight loss surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of rivaroxaban compared to enoxaparin for the prevention of venous thromboembolism (VTE) in morbidly obese patients who are candidates for bariatric surgery. The study is an open-label randomized controlled trial that aims to determine which medication is more effective in reducing the risk of post-operative blood clots. Given the rising prevalence of obesity and the associated risks of VTE, this research addresses a critical public health issue. Participants will be monitored for VTE incidence following their surgical procedures to assess the outcomes of each treatment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age: 20-60 years, both sexes.
* ASA physical status class I to III.
* BMI 35-50 kg/m²

Exclusion Criteria:

* Severe cardiac disorder
* chronic renal failure
* liver cirrhosis
* major psychological disorder

Where it's running

• Alexandria University
  Alexandria, Egypt Recruiting

Study contacts

• Principal investigator: sarah m elgamal, MD — Alexandria University
• Study coordinator: sarah m elgamal, MD
• Email: sarahelgamal1990@yahoo.com
• Phone: 01005496440

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Examining gut microbiota changes in patients undergoing metabolic surgery

  This study is testing how metabolic surgery affects gut bacteria and heart health in patients, especially focusing on the African American community, over the next 10 years.

  Recruiting Vanderbilt University Medical Center · Nashville, Tennessee · NCT05000996

• Factors that determine long-term success after bariatric surgery

  We will see which patient and surgical factors are linked to lasting weight loss in people who had bariatric surgery at least five years ago.

  Recruiting at 4 sites University Hospital, Lille · Arras and 3 other locations · NCT03517072

• TSBL-based vs BMI-based limb length in one-anastomosis gastric bypass

  This trial tests whether calculating the biliopancreatic limb length by total small bowel length (TSBL) helps weight loss and safety more than using standard BMI-based lengths in adults undergoing a single-center OAGB for obesity.

  Recruiting National Scientific Center of Surgery named after A.N.Syzganov · Almaty · NCT07796503

• Transcutaneous Nerve Stimulation to Help Breathing After Bariatric Surgery

  A randomized trial tests whether a skin-placed nerve stimulator can reduce diaphragmatic dysfunction after bariatric surgery in people with obesity.

  Recruiting Cairo University · Cairo and 1 other locations · NCT07569705

• Stress response with desflurane versus opioid-free TIVA during weight-loss surgery

  This study will test whether adding the inhaled anesthetic desflurane to opioid-free anesthesia changes the body's perioperative stress response in people having bariatric (weight-loss) surgery.

  Recruiting G.Gennimatas General Hospital · Athens · NCT07568938

• Gut stool tests after sleeve vs gastric bypass

  This study tests whether routine stool tests can reveal changes in gut function six months after sleeve gastrectomy or gastric bypass in adults with morbid obesity.

  Recruiting Cairo University · Cairo, Al-Manial Cairo · NCT07461610

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.