Clinical trial Recruiting at 1 site Interventional Ages 40 to 60

Comparing retro-walking and forward-walking on an underwater treadmill for knee osteoarthritis

Official title: Effect of Retro-walking Versus Forward-walking Training Using Underwater Treadmill on Pain and Function in Patients With Knee Osteoarthritis

Run by Cairo University · NCT06896032 · Data updated 2026-11-12

This study is testing whether walking backwards or forwards on an underwater treadmill helps people with knee osteoarthritis feel less pain and move better.

Quick facts

Study typeInterventional
Ages40 Years to 60 Years
SexAll
Enrollment60 (estimated)
SponsorCairo University
Academic / other
Locations2 sites (Cairo, Cairo Governorate and 1 other locations)
StatusRecruiting
StartedMarch 30, 2025
Main results expectedJune 30, 2025
Study endsJuly 25, 2025
Registry record updatedApril 16, 2025
Trial IDNCT06896032 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals aged 40-60 with mild to moderate unilateral knee osteoarthritis and a BMI between 25-35.

Probably not a fit

Patients with severe osteoarthritis, systemic inflammatory diseases, or other significant medical conditions may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of two different walking techniques—retro-walking and forward-walking—using an underwater treadmill on patients suffering from chronic knee osteoarthritis. A total of sixty participants will be recruited and divided into three groups to assess pain, function, and range of motion (ROM) improvements. The study aims to determine which walking method is more effective in alleviating symptoms associated with knee OA. Participants will undergo physical therapy interventions tailored to their assigned group.

Why it matters

Potential benefit: If successful, this study could provide a new, effective rehabilitation method for patients with knee osteoarthritis, improving their quality of life.

How similar studies have gone: While similar approaches have been explored, this specific comparison of retro-walking versus forward-walking in an underwater setting is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. 60 patients with chronic knee OA.
2. Age ranges from 40-60 years old of both genders.
3. body mass index (BMI) 25- 35kg/m2.
4. The degree of osteoarthritis was mild or moderate and have a Kellgren- Lawrence radiographic grade of of1-3.
5. unilateral knee osteoarthritis involvement.

Exclusion Criteria:

1. hydrophobia.
2. pregnancy.
3. infection.
4. psychiatric disorder.
5. haemorrhagic diathesis.
6. cardiac pacemaker.
7. all Subjects with deformity of hip, knee \& ankle.
8. any CNS or PNS involvement.
9. recent steroidal or intraarticular injections (3 months).
10. systemic inflammatory disease and bone malignancy.

Where it's running

  • cairo U
    Cairo, Cairo Governorate, Egypt
    Recruiting
  • cairo U
    Cairo, Cairo Governorate, Egypt
    Enrolling by invitation

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.