Comparing regional and general anesthesia for carotid surgery in stroke patients
The Study is Planned to Evaluate the Effectiveness and Safety of Two Types of Anesthesia (Regional and General) for Carotid Endarterectomy in 100 Patients With Acute Stage of Stroke: 50 Patients Will be Operated Under Regional Anesthesia and the Remaining 50 Patients Under General Anesthesia.
This study is testing whether regional anesthesia is safer and more effective than general anesthesia for stroke patients undergoing carotid surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 40 Years to 80 Years |
| Sex | All |
| Sponsor | Pirogov Russian National Research Medical University Academic / other |
| Locations | 1 site (Moscow) |
| Trial ID | NCT06175715 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness and safety of regional versus general anesthesia during carotid endarterectomy in patients experiencing acute ischemic stroke. A total of 100 patients will be enrolled, with 50 receiving regional anesthesia and 50 receiving general anesthesia. The study aims to assess perioperative complications, including the occurrence of ipsilateral ischemic strokes and other stroke types within 30 days post-surgery. The inclusion criteria focus on patients with specific neurological deficits and ischemic conditions.
Who should consider this trial
Good fit: Ideal candidates are patients with acute ischemic stroke in the middle cerebral artery territory and significant internal carotid artery stenosis.
Not a fit: Patients with contraindications for either type of anesthesia or those outside the specified time frame post-stroke may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could help determine the safest and most effective anesthesia method for stroke patients undergoing carotid endarterectomy.
How similar studies have performed: While there have been studies comparing anesthesia methods in various surgical contexts, this specific approach in acute ischemic stroke patients is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 1\. Ischemic stroke in the middle cerebral artery territory 2. Ipsilateral stenosis of the internal carotid artery more than 50% 3. Neurological deficit at the time of surgical treatment: the modified Rankin scale (mRs) score of 0-4 and the US National Institutes of Health (NIHSS) stroke scale score no more than 12 4. The size of the ischemia focus: no more than 1/3 in the territory of the middle cerebral artery brain supply 5. Terms of operation: from 1 to 28 days from the moment of ischemic stroke Exclusion Criteria: \-
Where this trial is running
Moscow
- Pryamikov Aleksandr — Moscow, Russia (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.